NEWS

From the bench to the boardroom

News from the Buck and beyond

Press Release . Oct 08, 2018

A new method to pinpoint genetic differences between species

Publishing in Nature Genetics, research from the Buck Institute lays the groundwork for the mapping of genes to traits throughout the plant and animal kingdoms...

news . Sep 04, 2018

Advanced Glycation End Products As Drivers of Age-Related Disease

Pankaj Kapahi makes his case to the research community and the public

Press Release . Aug 28, 2018

Tara Tracy joins faculty at Buck Institute

Neuroscientist studies synaptic dysfunction and cognitive decline in Alzheimer’s

Press Release . Aug 14, 2018

Three leaders in longevity biotechnology form a research collaboration

The Buck Institute, Juvenescence, and Insilico Medicine announce a research collaboration utilizing AI to discover and develop novel anti-aging therapeutics targeting a new molecular pathway and found Napa Therapeutics

Press Release . Jul 25, 2018

World’s first Center for Female Reproductive Longevity and Equality established at the Buck Institute for Research on Aging

A $6 million gift provides seed money to address a long-standing inequality: men can reproduce throughout their lifespan; but women's fertility begins to decline in their early 30's...

What I want people to know about the Buck is the incredible commitment and excitement that permeates the walls of this institution. We are pushing the frontiers in an area that is going to impact all of humanity. I cannot tell you exactly when this will happen, but I can tell you big discoveries will come out of the Buck.

Eric Verdin, MD, Buck Institute President and CEO

news . Jul 23, 2018

Buck faculty member Pankaj Kapahi spearheads mentoring efforts for disadvantaged children in India

Kapahi grew up in India with every advantage...

news . Jul 09, 2018

First patient treated with drug based on Buck research

Unity Biotechnology, which incubated at the Buck Institute, has treated the first patient in a Phase I clinical trial evaluating a drug to selectively eliminate senescent cells in moderate to severe osteoarthritis of the knee...

news . May 30, 2018

Judy Campisi elected to the National Academy of Sciences for her pioneering work on cellular senescence

How does great science happen, and how does a great scientist get her start? The answers might surprise you.

news . Apr 05, 2018

Largest “pan-cancer” genomics study spurs future efforts to enroll patients in specialized “basket” clinical trials

Buck professor Chris Benz is senior co-author of several papers publishing in Cell based on the Cancer Genome Atlas project.

news . Mar 13, 2018

Geriatrician-scientist John Newman, MD, PhD, joins the Buck faculty

Geriatrician and researcher in the field of aging poised to bridge gap between lab and clinical practice.

news . Jan 23, 2018

A Potential New Therapeutic Approach for Parkinson’s Disease

A potential new therapeutic approach for Parkinson’s disease.

news . Dec 07, 2017

Inhibiting TOR boosts regenerative potential of adult tissues

Rapamycin prevents age-related loss of stem cells

news . Nov 20, 2017

Taube Philanthropies Grants $750,000 to Buck Institute for Huntington’s Disease Research

Taube Philanthropies, one of the Bay Area’s foremost charitable organizations, has granted $750,000 to the Buck Institute for Research on Aging to support work performed by Dr...

news . Oct 05, 2017

Exceptional Early Career Scientist Joins the Buck with a $2.4M Federal Grant

Chuankai Zhou is awarded prestigious Early Independence Award from NIH

news . Sep 05, 2017

Ketogenic diet improves healthspan and memory in aging mice

Study on the effects of ketone bodies opens up new area of inquiry in research on aging.

news . Aug 29, 2017

Some women with history of preeclampsia have significantly lower risk for breast cancer

Researchers utilize samples from California Teachers Study to confirm protection comes via a common genetic variant

news . May 04, 2017

Large data set brings precision to breast cancer diagnosis and care

Buck Institute faculty Chris Benz, MD, is a co-author on a study finding genetic variations common in black women could improve outcomes, reduce recurrence

news . Feb 21, 2017

Longevity-promoting superstar gets revealed in Caenorhabditis reproducibility project

The Caenorhabditis Intervention Testing Program shows that genetic background and scientific methods impact efforts to identify compounds that affect longevity

news . Feb 06, 2017

Alpha-lipoic acid prevents kidney stones in mouse model of rare genetic disease

Buck Institute research leads to clinical trial for cystinuria at UCSF

news . Jan 17, 2017

Senescence promotes chemotherapy side effects and cancer relapse

Eliminating pro-inflammatory cells after treatment relieves symptoms in mice.

news . Jan 12, 2017

Improving the longevity of functionally integrated stem cells in regenerative vision therapy

Buck scientists restore long-term vision in blind mice, making a case for addressing the immune system’s role in rejecting transplanted cells

news . Jan 04, 2017

Real Estate Entrepreneur Bill Poland Chairs Buck Institute Board of Trustees

Prominent San Francisco commercial real estate developer Bill R...

news . Dec 13, 2016

Research in worms provides a model to study how the microbiome influences disease in humans

The interaction between bacteria and worms can be used to understand host-microbiome signals in humans that contribute to diseases such as type 2 diabetes and obesity

news . Dec 01, 2016

Buck Institute study provides neuronal mechanism for the benefits of fasting

The first molecular details are uncovered, in fruit flies, about how nutrient scarcity influences synapse function

news . Nov 18, 2016

BUCK ANNOUNCES NEW CEO AND $10 MILLION IN GIFTS TO FUEL GROWTH

ERIC VERDIN NAMED PERMANENT PRESIDENT AND CEO

news . Oct 28, 2016

Buck Institute Appoints Edward Lanphier President and CEO

The Buck Institute for Research on Aging (Buck Institute) today announced the appointment of Edward Lanphier as president and chief executive officer

news . Oct 18, 2016

Buck faculty Julie Andersen, PhD, receives grant from Michael J. Fox Foundation to study brain aging as a factor in Parkinson’s disease

Buck professor Julie Andersen, PhD, has received $200,000 from The Michael J...

news . Oct 18, 2016

A new look at vitamin D challenges the current view of its benefits

Research in C elegans shows the popular supplement engages longevity genes to increase lifespan and prevent the accumulation of toxic proteins linked to many age-related diseases

news . Oct 13, 2016

Research in worms provides path to study diabetic complications

Scientists find sensor for toxic molecules linked to excess blood sugar and identify natural compounds that may provide new therapies for serious health problems

news . Oct 13, 2016

Buck Institute’s Jennifer Garrison, Phd Receives $100,000 AFAR Grant for Junior Faculty to Advance Research in the Biology of Aging and Age-Related Diseases

As it commemorates its 35th anniversary, the American Federation for Aging Research (AFAR) is proud to award Jennifer Garrison, PhD, Assistant Professor, Buck Institute for Research on Aging, with an AFAR Grant for Junior Faculty...

news . Sep 15, 2016

Future therapeutics: drugs that stop free radicals at their source

Research at the Buck Institute yields molecules that prevent free radical production by cells

news . Aug 24, 2016

Buck faculty Jennifer Garrison, PhD, receives prestigious $2.5 million award from NIH

Five-year MIRA grant supports lab-based research on neuropeptide signaling

news . Jul 28, 2016

Buck Institute study sheds light on gender differences in diabetes and aging

All’s not fair in love and glucose intolerance

news . Jul 06, 2016

Improving on a broccoli-related compound yields a possible treatment for macular degeneration

Buck Institute study also shows that palmitoleic acid protects the retina from environmental damage in mouse models of disease.

news . Jul 05, 2016

Metformin as a potential treatment for a rare pediatric disorder

Study in human skin cells and mice shows widely-used diabetes drug reduces toxic acid levels in Maple Syrup Urine Disease

news . Jun 15, 2016

Pre and post testing show reversal of memory loss from Alzheimer’s disease in ten patients

Small trial from the Buck Institute and UCLA succeeds using systems approach to memory disorders

news . Jun 01, 2016

Buck researchers identify new “druggable” target for sporadic Parkinson’s disease

Research at the Buck Institute shows the same mechanisms that lead to neuronal cell death in mice genetically fated to develop Parkinson’s disease (PD) are involved in the much more common sporadic form of the age-related, neurodegenerative disorder that robs people of the ability to move normally...

news . May 26, 2016

Can we extend healthspan by altering the perception of food?

Tricking C elegans into a state of caloric restriction extends lifespan by 50% and suggests new targets for human pharmacology

news . May 17, 2016

Buck research may provide missing link in search for Parkinson’s disease therapeutics

Largest collection of induced pluripotent stem cell lines and related genomic assays from Parkinson’s patients provide a disease model which will be available to researchers world-wide

news . Mar 23, 2016

The Glenn Center for Biology of Aging Research Established at the Buck Institute

It is increasingly clear that inter-connected mechanisms drive age-related disease...

news . Feb 10, 2016

A new method furthers understanding of evolutionary genetics

Publishing in Nature, discovery helps unravel the mystery of ancient traits

news . Feb 10, 2016

Inhibiting age-related inflammation maintains healthy gut microbiota and extends lifespan

Blocking a well-known inflammatory pathway in the fly prevents abnormal changes in gut tissue, benefits gut bacteria and delays functional decline associated with age

news . Jan 22, 2016

The connection between excess iron and Parkinson’s disease

Excess iron impairs cellular recycling resulting in toxic oxidative stress

news . Jan 13, 2016

A surprising new role for ApoE offers explanation for its diverse range of effects, particularly in Alzheimer’s

Buck Institute/UCLA study finds that apolipoprotein E enters the nucleus and binds to promoter region of 1700 genes...

news . Dec 10, 2015

Signaling from dysfunctional mitochondria induces cellular senescence with a distinct secretory phenotype

Finding provides alternative explanation for the free-radical theory of aging and suggests new role for mitochondria in affecting physiology

news . Nov 30, 2015

Intracellular calcium integrates complex signaling to control stem cell activity

Seminal discovery, publishing in Nature, reveals new mode of stem cell regulation

news . Nov 18, 2015

Dietary restriction gives fruit flies a rhythm for a long life

Research on circadian clocks identifies critical role for peripheral clock genes in fat metabolism and aging and presents new targets for drug development

news . Oct 22, 2015

$1.25 million bequest funds first named professorship at Buck Institute

Buck Institute breast cancer researcher Christopher Benz, MD, received the Institute’s first named professorship following a $1...

news . Oct 16, 2015

Rapamycin prevents Parkinson’s in mouse model of incurable neurodegenerative disease

Buck Institute study reveals much broader role for Parkin in cellular dynamics, challenging current dogma in the field.

news . Oct 13, 2015

Buck Faculty Jennifer Garrison Announced as an Allen Institute for Brain Science 2015 Next Generation Leader

Assistant professor Jennifer Garrison, PhD, has been selected as one of this year’s six Next Generation Leaders at the Allen Institute for Brain Science...

news . Oct 05, 2015

Mapping the Genes that Increase Lifespan

Comprehensive study finds 238 genes that affect aging in yeast cells.

news . Jul 29, 2015

Surprising results in study of mitochondrial dysfunction in skin casts light on the free radical theory of aging

Scientists in the Campisi lab at the Buck Institute bred mice that produced excess free radicals that damaged the mitochondria in their skin

news . Jul 28, 2015

An imbalance of cellular bioenergetics in pancreatic beta-cells is linked to type 2 diabetes

Impaired activation of mitochondrial energy metabolism in the presence of glucose has been demonstrated in pancreatic beta-cells from patients with type 2 diabetes...

news . Jul 24, 2015

Low-dose lithium reduces side effects from most common treatment for Parkinson’s disease

Buck Institute research provides further validation that low-dose lithium could be repurposed as a therapy for the incurable neurodegenerative disorder

news . Jun 20, 2015

New paradigm for treating “inflammaging” and cancer

Intermittent dosing with rapamycin breaks inflammatory loop that fuels tumor relapse and age-related diseases

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Aug 14, 2018

Three leaders in longevity biotechnology form a research collaboration

July 25, 2018

$6 million donation to help Buck Institute study extending age of women’s fertility

Apr 6, 2018

The Scientist covers research from the Andersen lab detailing a new way to look at Parkinson’s disease pathology

Apr 6, 2018

Reclassifying cancers to improve treatment – the BBC interviews Professor Chris Benz about major studies appearing in Cell

Mar 27, 2018

Buck faculty John Newman talks to Wired – The Science behind the pursuit of youth

Apr 26, 2018

Buck Institute research suggests lithium may be effective in treating Parkinson’s disease

Mar 14, 2018

Interview With Aging Expert Dr. Julie K. Andersen

Jan 24, 2018

Cellular Senescence in Astrocytes May Play Central Role in Parkinson’s Disease

Here’s what’s happening

Upcoming events that feature Buck science

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Formal research seminars

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OCT 27, 2018

Thinking Structure

New Works by: Kirk Stoller, Linda Geary, Sabine Reckewell, Ann-Marie Stöhr, Andy Vogt, Ulrike Palmbach

OCT 27, 2018

North Bay Science Discovery Day

100 hands-on experiences for kids and kids at heart!

NOV 09, 2018

Bay Area Aging Meeting (BAAM)

Industry event

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MEDIA CENTER

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Buck Institute @BuckInstitute·

Can #AI help us catch Alzheimer’s before it progresses? Using data from the #Alzheimer’s Disease Neuroimaging Initiative, scientists have designed an algorithm that can predict cognitive decline and may drive preventative treatments. #livebetterlonger https://t.co/nLwrUhTd0F

Buck Institute @BuckInstitute·

How are companies using the basic #aging discoveries of Buck scientists to develop new therapies? The @Guardian discusses cellular senescence pioneered by our own Judith Campisi and the startups trying to target it. @UnityBiotech #livebetterlonger https://t.co/GChlLfrQm1

Buck Institute @BuckInstitute·

New study in @Cell_Metabolism reveals a previously unknown connection between a central component of the immune system, complement C3, and autophagy in pancreatic beta cells. #livebetterlonger https://t.co/KQ3JAl4X6N

UNITY Biotechnology @UnityBiotech·

Such a blast ringing the Opening Bell @nasdaq this morning! Thank you to everyone who has supported $UBX - our employees & Board members, investors, partners, family & friends – for helping us get to where we are today!

Buck Institute @BuckInstitute·

That look when your science turns into medicines that could help people #livebetterlonger. Congratulations to @UnityBiotech and Buck Professor Judy Campisi on ringing the Opening Bell @nasdaq today.

NEWS

From the bench to the boardroom

A new method to pinpoint genetic differences between species

Advanced Glycation End Products As Drivers of Age-Related Disease

Tara Tracy joins faculty at Buck Institute

Three leaders in longevity biotechnology form a research collaboration

World’s first Center for Female Reproductive Longevity and Equality established at the Buck Institute for Research on Aging

Three leaders in longevity biotechnology form a research collaboration

$6 million donation to help Buck Institute study extending age of women’s fertility

The Scientist covers research from the Andersen lab detailing a new way to look at Parkinson’s disease pathology

Reclassifying cancers to improve treatment – the BBC interviews Professor Chris Benz about major studies appearing in Cell

Buck faculty John Newman talks to Wired – The Science behind the pursuit of youth

Science VS podcast includes CEO Eric Verdin as it looks at the ketogenic diet

The Boston Globe does a feature piece on the field of aging research

Flushing out ‘zombie cells’ could help stave off Parkinson’s, study suggests

Event Highlights

Here’s what’s happening

Formal research seminars

Thinking Structure

North Bay Science Discovery Day

Bay Area Aging Meeting (BAAM)

MEDIA CENTER

Need more information about the Buck?

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