Female reproductive longevity and equality

Exploring the critical relationship between reproductive function and aging.

Our focus is aging

While aging research is seeing unprecedented acceleration, the area of women’s reproductive longevity has remained underappreciated. Thanks to a significant gift from Nicole Shanahan, the Buck is establishing the Center for Female Reproductive Longevity and Equality. This will be the first facility anywhere in the world focused solely on reproductive equality and longevity as it relates to aging and ending the threat of age-related disease.

Results from some recent small investigational studies suggest that there are several potential molecular mechanisms contributing to ovarian aging, including impaired DNA repair, metabolic/energetic disorders, and mitochondrial dysfunction. We are looking forward to building on these preliminary findings to further the understanding of the mechanisms of reproductive senescence and potentially develop strategies to prevent or delay ovarian aging.

Francesca E. Duncan, PhD

Associate Professor in Residence
Read more

Jennifer Garrison, PhD

Assistant Professor
Read more

Collaborating with the Buck

Learn more about how your company can work with Buck science and technology.

Learn more