Senescence and inflammation

It’s a feature of nearly every chronic disease. Some experts call this phenomenon inflamm-aging.

Our focus is aging

Chronic inflammation drives many age-related diseases, and the Buck is a pioneer in efforts to deal with it. Senescent cells, which stop dividing under stress, accumulate over our lifetime, secreting factors that cause inflammation and lead to tissue degradation. We helped develop a method that selectively clears senescent cells, and we incubated a company that is readying new drugs for clinical trials. We are also working on groundbreaking projects aimed at tackling senescence in the aging brain.

Julie Andersen, PhD

Professor
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Pierre-Yves Desprez PhD

Professor in Residence
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Francesca E. Duncan, PhD

Associate Professor in Residence
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David Furman, PhD

Associate Professor
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Malene Hansen, PhD

Chief Scientific Officer and Professor
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Pankaj Kapahi, PhD

Professor
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Simon Melov, PhD

Professor
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Birgit Schilling, PhD

Professor
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Eric Verdin, MD

President and Chief Executive Officer, Professor
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Daniel Winer Thumbnail image

Dan Winer, MD

Associate Professor
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Akos Gerencser, MD, PhD

Associate Research Professor
Director of the Morphology and Imaging Core
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Collaborating with the Buck

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