EVENT
2023 Agenda
May 19, 2023
Retrotransposons as agents of aging and disease
Stephen Helfand, MD
Associate Director for Research, Professor of Biology, Dept. of Molecular Biology, Cell Biology and Biochemistry, Brown University
Hosted by Pankaj Kapahi
May 26, 2023
An insulin/IGF receptor kinase insert domain regulates Drosophila lifespan through methionine cycle metabolic reprogramming
Marc Tatar, PhD
Professor, Department of Ecology & Evolutionary Biology, Brown University
Hosted by Dr. Gordon Lithgow and Dr. Julie Andersen
Sept 8, 2023
Encoding Memory in Amyloid
Kausik Si, PhD
Investigator & Scientific Director, Stowers Institute for Medical Research
Hosted by Kai Zhou
Sept 15, 2023
Title: TBA
Raphael de Cabo, PhD
Senior Investigator, Experimental Gerontology Section, NIA
Hosted by Pankaj Kapahi
Oct 6, 2023
Title: TBA
James Shorter, PhD
Professor of Biochemistry and Biophysics
University of Pennsylvania
Hosted by Kai Zhou
Distinguished Lecture Series (Past)
October 9, 2020
Uncovering the role of Alzheimer’s disease risk genes using stem cells and human brains
Li-Huei Tsai, PhD
Neuroscientist and Director of the Picower Institute for Learning and Memory
Department of Brain and Cognitive Sciences
Massachusetts Institute of Technology
Hosted by Tara Tracy
January 17, 2020
Signals and forces patterning the intestinal smooth muscle
Cliff Tabin
Chairman and Professor, Department of Genetics, Harvard Medical School; Adjunct Professor of Health Sciences & Technology, Massachusetts Institute of Technology
Hosted by Rachel Brem
April 12, 2019
Stem cells in silence, action and cancer
Elaine Fuchs
HHMI Investigator, Rebecca C. Lancefield Professor, Lab of Mammalian Cell Biology & Development, HHMI, The Rockefeller University
Hosted by Jennifer Garrison
FRS Speakers (Past)
May 5, 2023
Igniting an immune response to DNA with cGAS
Zhijian “James” Chen, PhD
Professor of Molecular Biology
University of Texas
Southwestern Medical Center
Hosted by Kai Zhou
April 14, 2023
Geroscience-Oriented Human Trials
Nicolas Musi, MD
Professor and Director, Center on Aging and Metabolism, Cedars-Sinai Medical Center
Hosted by Julie Andersen and Gordon Lithgow
Mar 17, 2023
Molecular effectors of physical activity
Jonathan Long, PhD
Assistant Professor of Pathology and ChEM-H Institute Scholar, Stanford University
Hosted by Pankaj Kapahi
March 3, 2023
Fertility, Immunity & Longevity: Burning Fat, Breaking Dogmas
Arjumand Ghazi, PhD
Associate Professor of Pediatrics, Developmental Biology & Physiology, University of Pittsburg, School of Medicine
Hosted by Jennifer Garrison
Feb 17, 2023
Conditional mitochondrial mRNA localization: connecting mitochondrial composition to growth and metabolism
Brian Zid, PhD
Assistant Professor, Dept. of Chemistry & Biochemistry, UC San Diego
Hosted by Pankaj Kapahi
Jan 13, 2023
Impact of endocrine aging on the human brain
Emily Jacobs, PhD
Associate Professor of Psychological & Brain Sciences, Neuroscience Research Institute, University of California, Santa Barbara
Hosted by Jennifer Garrison
Nov 18, 2022
RNA Editing, Innate Immunity, and Inflammation
Jin Billy Li, PhD
Associate Professor of Genetics, Stanford University
Hosted by Kai Zhou
Oct 7, 2022
Alzheimer’s Disease is caused by the chronic dysregulation and weakening of innate immunity and the BBB via the underexpression, degradation and inactivation of innate immune proteins including LL-37 and ApoE
Annelise Barron, PhD
Associate Professor of Bioengineering, Stanford University
Hosted by Julie Andersen
March 4, 2022
Mitigating Brain Aging
Joel Kramer, PsyD
Professor of Neuropsychology in Neurology
Director of the Memory and Aging Center Neuropsychology Program, UCSF
Hosted by Tara Tracy
Jan 21, 2022
The 4D Nucleome of Gene Regulation in Stem Cell and Regeneration
Yauri Diao, PhD
Assistant Professor of Cell Biology, Duke University School of Medicine
Hosted by Kai Zhou, PhD
June 4, 2021
Inosine RNA modifications in oocytes
Pavla Brachova, PhD
Research Assistant Professor, University of Kansas Medical Center, Department of Molecular and Integrative Physiology
Hosted by Buck Assistant Professor, Jennifer Garrison, and Assistant Professor in Residence, Francesca Duncan
May 21, 2021
Mitochondrial Behavior
Jodi Nunnari, PhD
Distinguished Professor and Chair, Molecular and Cellular Biology, University of California, Davis
Hosted by Buck Fellow, Kai Zhou
May 14, 2021
Niche control of stem cell self-renewal and differentiation
Ting Xie, PhD
Division Head and Kerry Holdings Professor of Science, The Hong Kong University of Science and Technology
Hosted by Buck Fellow, Kai Zhou
April 16, 2021
Dynamics of muscle stem cells in tissue growth and repair
Alessandra Sacco, PhD
Associate Professor
Development, Aging and Regeneration Program
Neuroscience and Aging Research Center, Sanford Burnham Prebys, Medical Discovery Institute
Hosted by Buck Professor, Simon Melov
April 9, 2021
Pharmacologic Adaptation of Proteostasis to Ameliorate Aging-associated Degenerative Diseases
Jeff Kelly, PhD
Lita Annenberg Hazen Professor
of Chemistry, The Scaggs Institute for Chemical Biology / The Scripps Research Institute
Hosted by Buck Fellow, Kai Zhou
April 2, 2021
Anatomical Biology as a Key into Alzheimer’s Disease and Cognitive Aging
Scott A. Small, MD
Director, Alzheimer’s Disease Research Center
Boris and Rose Katz Professor of Neurology
Columbia University, NY
Hosted by Buck professor, Pankaj Kapahi
March 19, 2021
Immunesenescence: Consequences within and without the immune system
Janet Lord, PhD
Director of the Institute of Inflammation and Ageing, University of Birmingham, England
Hosted by Buck Professor, Gordon Lithgow
March 5, 2021
New ways to prevent protein aggregation inside and outside the cell
Della C. David, PhD
Interfaculty Institute of Biochemistry, University of Tuebingen, Germany
Hosted by Buck Professor, Gordon Lithgow
February 26, 2021
Intertwined Roles of Two Parkinson’s Disease Genes in Autophagy of Mitochondria and Inflammation
Richard J. Youle, PhD
Senior Investigator, Biochemistry Section, Porter Neuroscience Research Center, National Institute of Neurological Disorders & Stroke, Bethesda, MD
Hosted by Buck Fellow, Kai Zhou
January 15, 2021
Systems Approach to Identify Resilience-based Targets for Aging and Alzheimer’s
Catherine Kaczorowski, PhD
Associate Professor and Evnin Family Chair in Alzheimer’s Research, The Jackson Laboratory
Hosted by Buck Professor, Pankaj Kapahi
November 20, 2020
Targeting hypothalamic microglia to regulate energy and glucose homeostasis
Martin Valdearcos Contreras, PhD
Assistant Adjunct Professor, Diabetes Center, UCSF
Hosted by Buck Professor, Pankaj Kapahi
October 23, 2020
Perception and response to metabolic stress
Scott Leiser, PhD
Assistant Professor Molecular & Integrative Physiology and Internal Medicine, University of Michigan
Hosted by Jennifer Garrison
September 18, 2020
Counting mitochondria via the mitochondrial UPR: Do old cells lose count?
Cole Haynes, PhD
Professor of Molecular, Cell and Cancer Biology, Univ. of Massachusetts Medical School
Hosted by Kai Zhou
September 11, 2020
Mutagenesis screens define unexpected roles of metabolism and protein synthesis in longevity
Martin Denzel, PhD
Professor of Metabolic and Genetic Regulation of Ageing, Max Planck Institute for Biology of Ageing
Hosted by Jennifer Garrison
September 4, 2020
How neurons bend without breaking
Miriam Goodman, PhD
Professor and Chair of Molecular and Cellular Physiology, Stanford University
Hosted by Jennifer Garrison
August 21, 2020
From Football Players To Aging Brains: The Role of The Blood Brain Barrier
Daniela Kaufer, PhD
Associate Dean, Biological Sciences and Professor, Department of Integrative Biology and the Helen Wills Neuroscience Institute, University of California, Berkeley.
Hosted by Eric Verdin
July 17, 2020
Cellular recycling: role of autophagy in aging and disease
Malene Hansen, PhD
Professor, Faculty Advisor, Postdoctoral Training and Associate Dean, Graduate School for Biomedical Sciences, Sanford Burnham Prebys Medical Discovery Institute
Hosted by Eric Verdin
February 21, 2020
Interactions and Polymorphisms of Protein Aggregates in Neurodegenerative Disease: Implications for Drug Development
Rakez Kayed, PhD
Professor of Neurology, Neuroscience, Cell Biology & Anatomy, Mitchell Center for Neurodegenerative Diseases, University of Texas Medical Branch
Hosted by Tara Tracy
February 7, 2020
Mechanisms of pathogenesis tauopathies
Karen Duff, PhD
Professor, UK Dementia Research Institute at UCL, University College London
Hosted by Tara Tracy
January 24, 2020
Metabolic Signatures of Mating, Sex Peptide and Mifepristone/RU486 in Female Drosophila
John Tower, PhD
Professor of Biological Sciences, University of Southern California
Hosted by Pejmun Haghighi
January 10, 2020
Making a break for it: meiotic DSBs and germline DNA repair
Judith Yanowitz, PhD
Associate Professor, Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Research Institute and University of Pittsburgh School of Medicine
Hosted by Jennifer Garrison
November 15, 2019
Fast Mimicking Diets, Regeneration, and Age-related Diseases
Valter Longo, PhD
Edna M. Jones Professor of Gerontology, Professor of Biological Sciences, USC Longevity Institute
Hosted by Eric Verdin
November 8, 2019
Messenger RNA translation and oocyte competence to develop as an embryo: a genome-wide perspective
Marco Conti, MD
Professor & Director, Fred Gellert Chair in Reproductive Medicine & Biology, Center for Reproductive Sciences and the Eli and the Edythe Broad Center for Regeneration Medicine and Stem Cell Research, UCSF
Hosted by Jennifer Garrison and Lei Lei
November 1, 2019
Lipids and the demise of neurons
Hugo Bellen, DVM, Ph.D
Investigator and Professor, Departments of Molecular & Human Genetics, Neuroscience, and Neurological Research Instistute, HHMI and Baylor College of Medicine
Hosted by Pankaj Kapahi
October 11, 2019
Developmental Origins of Reproductive Aging and Infertility
Aleksander Rajkovic, MD, PhD
Stuart Lindsay Distinguished Professor in Experimental Pathology I, Department of Pathology, Dept. of Obstetrics, Gynecology & Reproductive Sciences, UCSF
Hosted by Jennifer Garrison
October 4, 2019
Systems Biology of the Mitochondria in Aging
Pinchas Cohen, MD
Dean, USC Leonard Davis School of Gerontology
University of Southern California
Hosted by Julie Andersen
March 8, 2019
Targeting Dysregulated Neuroinflammation in Alzheimer’s Disease
Linda Van Eldik, PhD
Director, Sanders-Brown Center on Aging University of Kentucky
Hosted by Lisa Ellerby
March 1, 2019
C. elegans discriminate colors without eyes or opsins
Michael Nitabach, PhD, JD
Professor of Cellular and Molecular Physiology, Genetics, Neuroscience, Yale University
Hosted by Jennifer Garrison
February 22, 2019
Genomic parasites and aging
Vera Gorbunova, PhD
Doris Johns Cherry Professor, Professor of Biology, Assoc. Professor of Oncology, University of Rochester
Hosted by Judy Campisi
February 8, 2019
Messenger Metabolites in Longevity Regulation
Meng Wang, PhD
Investigator, HHMI
Professor, Robert C. Fyfe Endowed Chair on Aging, Baylor College of Medicine
Hosted by Kai Zhou
January 25, 2019
To sleep or not to sleep: How the brain decides to wake us up
Luis de Lecea, PhD
Professor, Psychiatry & Behavioral Sciences, Stanford School of Medicine
Hosted by Jennifer Garrison
December 7, 2018
ER proteostasis unbalance: from aging to neurodegenerative diseases
Claudio Hetz, PhD
Biomedical Neuroscience Institute, Faculty of Medicine, Center for Geroscience, Brain Health & Metabolism, University of Chile, Dept. of Immunology and Infectious Diseases, Harvard School of Public Health; Adjunct Professor, Buck Institute
Hosted by Eric Verdin
November 30, 2018
Modeling Human Development Using Insights from Organoids and Embryos
Jason Spence, Ph.D
Associate Professor, Dept. of Internal Medicine
Dept. of Cell and Development Biology, University of Michigan
Hosted by Lisa Ellerby
November 12, 2018
Modeling of Human Neurological/Psychiatric Disorders using iPS cells and Transgenic Non-Human Primates
Hideyuki Okano, MD, PhD
Dean, Keio University Graduate School of Medicine & Professor, Dept. of Physiology
Tokyo, Japan
Hosted by Lisa Ellerby
October 26, 2018
Ovarian aging and the menopause: evaluating strategies to prevent or delay ovarian failure
Dori Woods, PhD
Assistant Professor, Biology, Northeastern University
Hosted by Judy Campisi
Octobre 12, 2018
Turning the Oxygen Dial as a Therapy: Hypoxia as a Treatment for Mitochondrial Dysfunction
Isha Jain, PhD
Sandler Faculty Fellow, UCSF
Hosted by Pankaj Kapahi
October 5, 2018
The genomics of flightlessness in birds
Scott V. Edwards, PhD
Alexander Agassiz Professor of Organismal and Evolutionary Biology, Harvard University
Hosted by Rachel Brem
Septemeber 28, 2018
Beyond Sarcopenia
Stephen Kritchevsky, Ph.D
Professor of Internal Medicine & Translational Research (with tenure), Section on Gerontology
& Geriatric Medicine, Department of Internal Medicine,Wake Forest School of Medicine
Winston-Salem, NC
Hosted by John Newman
September 21, 2018
A genetic model of rapid life-history evolution in the sea
Matthew Rockman, PhD
Assistant Professor, Dept. of Biology and Center for Genomics and Systems Biology, NYU
Hosted by Rachel Brem
September 7, 2018
On the Road to New Therapies for Intractable Epilepsies
Scott Baraban, PhD
Professor & William K. Bowes Jr. Endowed Chair in Neuroscience Research, Neurological Surgery
Weill Institute for Neurosciences, UCSF
Hosted by Lisa Ellerby
July 9, 2018
Enhanced protein turnover as a healthy aging strategy
Liesbet Temmerman, PhD
Assistant Professor, Department of Biology
Ku Leuven, Belgium
Hosted by Jennifer Garrison
June 1, 2018
Proteostasis and Inflammation: Converging Pathways in Neurodegeneration
Li Gan, PhD
Professor, Neurology, Associate Director & Senior Investigator, Gladstone Institute of Neurological Disease, UCSF
Hosted by Eric Verdin and Pankaj Kapahi
May 11, 2018
Cellular heterogeneity in response to chemotherapy or micro-environmental signals
Steven Altschuler, PhD
Professor, UCSF School of Pharmacy
Hosted by Christopher Benz
Joint seminar with Lani Wu, PhD
May 11, 2018
Cellular heterogeneity in response to chemotherapy or micro-environmental signals
Lani Wu, PhD
Professor, UCSF School of Pharmacy
Hosted by Christopher Benz
Joint seminar with Steven Altschuler, PhD
April 27, 2018
TAF1 and X-Linked Dystonia- Parkinsonism
Cristopher Bragg, PhD
Assistant Professor, Neurology, Massachusetts General Hospital and Harvard Medical School
Hosted by Lisa Ellerby
March 30, 2018
Stem cells and organ regeneration in immortal planarian flatworms
Carrie Adler, PhD
Principal Investigator, Dept. of Molecular Medicine, College of Veterinary Medicine Cornell University
Hosted by Jennifer Garrison
March 23, 2018
Building Hearts and Heart Parts
Kit Parker, PhD
Tarr Family Professor of Bioengineering & Applied Physics, Wyss Institute for Biologically-Inspired Engineering, Harvard Stem Cell Institute, Harvard School of Engineering and Applied Sciences, Harvard University
Hosted by Simon Melov
March 16, 2018
What is RNAi good for? Lessons from flies and mice, tales of sex and blood
Eric Lai, PhD
Professor, Memorial Sloan Kettering Cancer Center, New York
Hosted by Pejmun Haghighi
March 9, 2018
A synaptic basis of Age-Induced Memory Decline
Stephan Sigrist, PhD
Professor, Institute of Biology, Freie Universtät Berlin & Neurocure, Charité University Medicine Berlin
Hosted by Pejmun Haghighi
March 2, 2018
Skeletal Muscle Stem Cells: Regeneration and Aging
Andrew Brack, PhD
Associate Professor, Department of Orthopaedic Surgery, UCSF
Hosted by Professor Pejmun Haghighi and Postdoc Harshi Peiris
SHARE EVENT
Directions
The Buck Institute is located 25 miles north of the Golden Gate Bridge.
San Francisco Airport/San Francisco/South Bay:
- Take Highway 101 North across the Golden Gate Bridge
- Take the last Novato exit — Atherton/San Marin Drive (just north of the DeLong exit)
- Turn left at the stoplight, and go west over the freeway overpass
- Get in the right lane, and turn right at the second stoplight onto Redwood Boulevard
- Go approximately ½ mile, and turn left onto Buck Center Drive
- At the top of the hill, turn left into the Visitor Parking Lot
Berkeley/Oakland/Oakland International Airport:
- Take Highway 80 to Highway 580 West, and cross the Richmond/San Rafael Bridge
- Take 580 until it merges with Highway 101 North in San Rafael
- Take the last Novato exit — Atherton/San Marin Drive (just north of the DeLong exit)
- Turn left at the stoplight, and go west over the freeway overpass
- Get in the right lane, and turn right at the second stoplight onto Redwood Boulevard
- Go approximately ½ mile, and turn left onto Buck Center Drive
- At the top of the hill, turn left into the Visitor Parking Lot
From Sonoma County, take Highway 101 South:
- Take the first Novato exit (Atherton/San Marin Drive)
- Turn right at the stoplight, and stay in the right lane
- Take an immediate right onto Redwood Boulevard
- Go approximately ½ mile, and turn left onto Buck Center Drive
- At the top of the hill, turn left into the Visitor Parking Lot
Support the Buck
We rely on donations to support the science that we believe will add years to people's lifespan and decades to their healthspan.