The Buck Institute

Live better longer.

Working to create a world where everyone can have
healthy minds and healthy bodies at every age.

Learn More

Our Faculty

A mission-driven community
of investigators

The Buck is a collective of the world’s top scientists in the field of aging who are sharing their methods and
expertise to find ways to help everyone lead fuller, healthier lives by ending age-related disease.

Learn More

Our Research

Advancing the frontiers
of research on aging

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

Learn More

OUR MISSION

Our mission is to end the threat of age-related disease for this and future generations

We believe it is possible for people to enjoy their lives at 95 as much as they do at 25, and to achieve that, we’re seeking a more comprehensive understanding of the biology of aging itself.

Featured News

Advancing the frontiers
of aging research

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

Press Release

Buck researchers uncover intriguing connection between diet, eye health and lifespan

Buck researchers uncover an intriguing connection between diet, eye health and lifespan in Drosophila

Press Release

Buck Scientists Highlight New Perspective in How Immunity is Fine-Tuned through Mechanics

Introducing a new scientific discipline: Mechanoimmunlogy

blog

The Obesity Society says we need to change the way we talk about obesity

Buck professor Pankaj Kapahi agrees

Learn more about our research

“What I want people to know about the Buck is the incredible commitment and excitement that permeates the walls of this institution. We are pushing the frontiers in an area that is going to impact all of humanity. I cannot tell you exactly when this will happen, but I can tell you big discoveries will come out of the Buck.”

Eric Verdin, MD, Buck Institute President and CEO

Featured News

News

The Buck’s Impact Circle supports a first-ever pilot study to look at the effects of a ketogenic supplement in older adults

This year the Buck’s Impact Circle chose to support the first-ever clinical study to be done at the Buck Institute.
Press Release

Buck Institute scientists uncover a new role for blood-brain barrier in neuron function and damage

Findings open up a potential new avenue for therapies aimed at countering neurodegeneration
Press Release

Buck Scientist Uncovers Clues to Aging in Mitochondria

Understanding how the process starts can point to new directions in aging research
Press Release

A naturally-occurring metabolite is a potent senolytic in both mice and human cell culture

25-hydroxycholesteral shows particular efficacy in skeletal muscle

Press Release

Buck Institute scientists uncover a new role for blood-brain barrier in neuron function and damage

Findings open up a potential new avenue for therapies aimed at countering neurodegeneration
Read more
Press Release

Buck Scientist Uncovers Clues to Aging in Mitochondria

Understanding how the process starts can point to new directions in aging research
Read more
Press Release

A naturally-occurring metabolite is a potent senolytic in both mice and human cell culture

25-hydroxycholesteral shows particular efficacy in skeletal muscle
Read more
View more news

Event Highlights

Here’s what’s happening

Upcoming events at the Buck

Service Animal Accommodation
Ongoing

Formal Research Seminars

FRS talks are being held via Zoom by invitation only.
Read more
See all events
Buck Institute @buckinstitute ·

Congrats to the Haghighi lab! Study in @PNASNews uncovers a new role for the blood-brain barrier in neuron function and damage. Findings in #Drosophila open up a potential new avenue for therapies aimed at countering #neurodegeneration. https://www.buckinstitute.org/news/buck-institute-scientists-uncover-a-new-role-for-blood-brain-barrier-in-neuron-function-and-damage/

Buck Institute @buckinstitute ·

Science says there is a best way to take pills! Researchers @JohnsHopkins say pills dissolve much faster when we lay on our right side to take them. They tested four postures.  To see which one is worst go to: https://www.eurekalert.org/news-releases/961853

UNITY Biotechnology @unitybiotech ·

Today we announced positive data from the Ph 2 BEHOLD study of UBX1325 in diabetic macular edema. The 12- and 18-week results are a promising step in validating our #senolytic platform and supports the potential of UBX1325 in retinovascular diseases. https://bit.ly/3vY6V2o

Buck Institute @buckinstitute ·

Thank you Navigage for funding the USC-Buck PhD Program for over 5 years now! We're so grateful for their continuous support of our graduate students who do amazing work at Buck.
From left to right: Vickie Hatos, @beappbeapp, Sidharth Madhavan, Judy Vallas, @jenngarrison

Buck Institute @buckinstitute ·

Feeling exhausted after hours of intense cognitive work is not an illusion. Study in @CurrentBiology shows long bouts of thinking hard causes potentially toxic byproducts to build up in the prefrontal cortex, which alters your control over decisions. https://www.eurekalert.org/news-releases/960845

Visit the
Buck Institute

Come and share in the excitement. Our doors are open, and we love talking about our science.

SUPPORT THE BUCK

Join the fight against age-related diseases

You don’t have to be a scientist to make an important contribution to research on aging. We rely on donations to support the science that we believe will add years to people’s lifespan and decades to their healthspan.

Learn more