Can getting rid of senescent cells in the brain reduce memory loss?
A special guest blog from Alejandro Lopez-Ramirez, Lab Manager in the Ellerby lab and Lauren Wimer, Dominican University of California graduate student in the Kapahi lab.
Read about how Advait Thaploo, winner of the high school Summer Scholar blog contest, spent the summer discovering a new way to induce cellular senescence
Hot of the Buck blog press! Read how scientists are leveraging #iPSC technology to improve aging #livebetterlonger https://www.buckinstitute.org/blog/aging-is-inevitable-but-lets-make-it-better/
Deficiency in the DNA repair protein ERCC1 triggers a link between #senescence and apoptosis in human fibroblasts and mouse skin by Judith Campisi's group @BuckInstitute https://onlinelibrary.wiley.com/doi/full/10.1111/acel.13072
The t-loop sounds like a complex metro rail system but it’s actually a vital and dynamic #telomerestructure that helps protect #DNA. New work in @nature provides insights into how t-loops are regulated to wind and unwind at the right time #livebetterlonger https://www.eurekalert.org/pub_releases/2019-11/tfci-cru111119.php
#autophagy is usually good, but maybe you don’t want too much recycling when #DNA is loose in the cell, like during #mitosis. New work shows CDK1, not mTORC1, works to suppress autophagy during mitosis https://zcu.io/0eHx #livebetterlonger
Yes, google, we did mean #elovanoids and not flavonoids. Research from med school at @LSUHealthNO finds elovanoids (class of compounds from fatty acids) can act as #senolytics & protect against models of #Alzheimers & #maculardegeneration #livebetterlonger https://zcu.io/n0PJ
