From the bench to the boardroom

News from the Buck and beyond
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Aging is inevitable, but let’s make it better

Scientists are working toward developing treatments that use Dr...
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The Microbiome: you and your trillion little friends

Eric dives into the the emerging science of the microbiome and how it evolves during aging
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Cellular Housekeeping: How autophagy models in mice could lead to treatment in humans

A post from three graduate students about new possibilities for promoting autophagy
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Nature Nurtures: Food is the Best Source for Vitamins

Buck CEO Dr. Eric Verdin discusses the best source for vitamins...
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Can getting rid of senescent cells in the brain reduce memory loss?

A special guest blog from Alejandro Lopez-Ramirez, Lab Manager in the Ellerby lab and Lauren Wimer, Dominican University of California graduate student in the Kapahi lab.
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Ageism in Medical Care: Another Data Set to Improve Healthy Aging

Research that combats ageism will be an important part of improving healthy aging
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Cellular Senescence: A Contradictory Condition

Read about how Advait Thaploo, winner of the high school Summer Scholar blog contest, spent the summer discovering a new way to induce cellular senescence
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Some Evidence-Based Answers to Your Frequently-Asked Questions: A 3-Part Series

Part 3 of a 3 part series: Ketogenic diet and aging
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Do Wildfires Impact How We Age?

A special guest blog from Anja Holtz, Research Associate in the Schilling lab
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Here’s what’s happening

Upcoming events at the Buck

Ongoing

Formal Research Seminars

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Hot of the Buck blog press! Read how scientists are leveraging #iPSC technology to improve aging #livebetterlonger https://www.buckinstitute.org/blog/aging-is-inevitable-but-lets-make-it-better/

Deficiency in the DNA repair protein ERCC1 triggers a link between #senescence and apoptosis in human fibroblasts and mouse skin by Judith Campisi's group @BuckInstitute https://onlinelibrary.wiley.com/doi/full/10.1111/acel.13072

The t-loop sounds like a complex metro rail system but it’s actually a vital and dynamic #telomerestructure that helps protect #DNA. New work in @nature provides insights into how t-loops are regulated to wind and unwind at the right time #livebetterlonger https://www.eurekalert.org/pub_releases/2019-11/tfci-cru111119.php

#autophagy is usually good, but maybe you don’t want too much recycling when #DNA is loose in the cell, like during #mitosis. New work shows CDK1, not mTORC1, works to suppress autophagy during mitosis https://zcu.io/0eHx #livebetterlonger

Yes, google, we did mean #elovanoids and not flavonoids. Research from med school at @LSUHealthNO finds elovanoids (class of compounds from fatty acids) can act as #senolytics & protect against models of #Alzheimers & #maculardegeneration #livebetterlonger https://zcu.io/n0PJ