Live better longer.

Working to create a world where everyone can have
healthy minds and healthy bodies at every age.

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A mission-driven community
of investigators

The Buck is a collective of the world’s top scientists in the field of aging who are sharing their methods and
expertise to find ways to help everyone lead fuller, healthier lives by ending age-related disease.

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Advancing the frontiers
of research on aging

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

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Our mission is to end the threat of age-related disease for this and future generations

We believe it is possible for people to enjoy their lives at 95 as much as they do at 25, and to achieve that, we’re seeking a more comprehensive understanding of the biology of aging itself.

Advancing the frontiers
of aging research

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

The first non-invasive biomarker to track and verify efficacy of senolytic drugs

The discovery and development of a lipid-metabolite biomarker is expected to facilitate research and clinical trials of drugs that target multiple age-related diseases

Huntington’s disease: Modulating rapamycin target protein FKBP51 pathway promotes autophagy, lowering Huntingtin protein

Experiments with small molecule has implications for research on aging.

Making Research Fair and Equitable

Read up on racial disparities in clinical trials and steps we can take to make sure that gains in healthspan are shared equally.

“What I want people to know about the Buck is the incredible commitment and excitement that permeates the walls of this institution. We are pushing the frontiers in an area that is going to impact all of humanity. I cannot tell you exactly when this will happen, but I can tell you big discoveries will come out of the Buck.”

Eric Verdin, MD, Buck Institute President and CEO

Chronic viral infections can have lasting effects on human immunity, similar to aging

Researchers identify signatures of immune dysfunction that are shared in aging and chronic viral infections of HIV and Hepatitis C

The Buck Impact Circle Supports Project Aimed at Understanding Vulnerabilities and Resilience in the Aging Brain

The group awarded more than $100,000 to junior faculty members Kai Zhou, PhD and Tara Tracy, PhD

Special webinar will launch OVA, a new membership program for those interested in women’s health

Ovaries show signs of aging decades before other tissues. Women’s reproductive organs are considered geriatric in their early 30’s...
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Here’s what’s happening

Upcoming events at the Buck

Service Animal Accommodation
Ongoing

Formal Research Seminars

FRS talks are being held via Zoom by invitation only.

Another shout out for #metformin! In studies in mice the common diabetes drug (which may slow aging) shows promise as a treatment for COVID-19 lung inflammation. Metformin inhibited IL-1B and inflammasome assembly in immune cells found in the lungs.
https://www.eurekalert.org/pub_releases/2021-06/uoc--cdd060821.php

Meet our scientists! Brazilian postdoc @su_benitez models Alzheimer`s in flies & found specific signaling pathway which is over-activated. Preliminary experiments show same over-activation happens in mice with Alzheimer`s. She's now testing a drug that modulates this pathway.

Thank you, #nakedmolerat paper. We needed you to make it through the rest of the week! Nice summary of of what we know so far about these remarkable creatures coming from @UniofBradford https://www.eurekalert.org/pub_releases/2021-06/uob-cnm061021.php

In our GLI #mentor appreciation post this week we thank Prof. Julie Anderson of @BuckInstitute & Prof. Yuli Tamir of @shenkar_m for their generosity with their time. Thank you for imparting your wisdom to our students!

#global #leadership #initiative #gli2021 #studentdevelopment

Learning a new language, or how to play the guitar? Give yourself a break – at least a short one! A study from #NIH shows that breaks may help our brains learn new skills. https://www.nih.gov/news-events/news-releases/study-shows-how-taking-short-breaks-may-help-our-brains-learn-new-skills

Visit the
Buck Institute

Come and share in the excitement. Our doors are open, and we love talking about our science.

Join the fight against age-related diseases

You don’t have to be a scientist to make an important contribution to research on aging. We rely on donations to support the science that we believe will add years to people’s lifespan and decades to their healthspan.

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