Live better longer.

Working to create a world where everyone can have
healthy minds and healthy bodies at every age.

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A mission-driven community
of investigators

The Buck is a collective of the world’s top scientists in the field of aging who are sharing their methods and
expertise to find ways to help everyone lead fuller, healthier lives by ending age-related disease.

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Advancing the frontiers
of research on aging

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

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Our mission is to end the threat of age-related disease for this and future generations

We believe it is possible for people to enjoy their lives at 95 as much as they do at 25, and to achieve that, we’re seeking a more comprehensive understanding of the biology of aging itself.

Advancing the frontiers
of aging research

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

Tissue stiffness likely drives immune responses in many chronic diseases

Buck research points to the possibility of new immunotherapeutics and highlights critically needed changes in experimental techniques

Buck Institute Names Malene Hansen as Chief Scientific Officer

Dr. Malene Hansen is joining the Buck as our new Chief Scientific Officer! Buck CEO Eric Verdin sums it up: “She is an extraordinary scientist with the background, vision, and skills to enhance our leadership position and to accelerate our mission”

Chronic inflammation causes a reduction in NAD+

Buck research links hallmarks of aging: senescent cells activate CD38 which degrades NAD+, a key metabolite implicated in age-related decline

“What I want people to know about the Buck is the incredible commitment and excitement that permeates the walls of this institution. We are pushing the frontiers in an area that is going to impact all of humanity. I cannot tell you exactly when this will happen, but I can tell you big discoveries will come out of the Buck.”

Eric Verdin, MD, Buck Institute President and CEO

Buck postdoc Nathan Basisty wins a prestigious career-boosting award from the NIH

With both of his Buck mentors describing him as an “exceptional scientist” and a “generous and valuable collaborator,” postdoc Nate Basisty is poised to take a huge leap in his career, thanks to a prestigious and highly competitive Pathway to Independence Award from the National Institutes of Health.

The Buck is awarded three federal grants to target aging to prevent or cure Alzheimer’s disease.

The Buck is thrilled to announce that we have received nearly $10M in funding from the NIH for a geroscience approach to developing treatments for Alzheimers.

A metabolite produced by the body increases lifespan and dramatically compresses late-life morbidity in mice

Alpha-ketaglutarate improves several measures of healthspan in double-blind study
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Here’s what’s happening

Upcoming events at the Buck

Service Animal Accommodation

Formal Research Seminars

FRS talks are being held via Zoom by invitation only.

Buck job alert! Schilling Lab seeking Postdoc for innovative research aimed at understanding biological and chemical processes common to both age-related diseases and aging. Work w/ cutting edge technologies in liquid chromatography-mass spectrometry.

Exciting stuff from @KroganLab

Come for the #chronicinflammation and #exercise news, stay for the decade-in-development lab-grown muscle info from @DukeU! Simulated exercise in these muscles almost eliminates the chronic inflammation caused by interferon gamma application.

New Buck job alert! The Ellerby lab at the Buck Institute is looking for an Administrative Lab Manager with a background in molecular biology techniques, admin/managerial experience, and some hands-on practice in a scientific laboratory.

Be honest, you totally have a guesstimate about your own lifespan...maybe it's not all just guessing. It'd be cool to see a competition comparing our own predictions to emerging molecular and AI tools!

Visit the
Buck Institute

Come and share in the excitement. Our doors are open, and we love talking about our science.

Join the fight against age-related diseases

You don’t have to be a scientist to make an important contribution to research on aging. We rely on donations to support the science that we believe will add years to people’s lifespan and decades to their healthspan.

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