Live better longer.

Working to create a world where everyone can have
healthy minds and healthy bodies at every age.

Learn More

A mission-driven community
of investigators

The Buck is a collective of the world’s top scientists in the field of aging who are sharing their methods and
expertise to find ways to help everyone lead fuller, healthier lives by ending age-related disease.

Learn More

Advancing the frontiers
of research on aging

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

Learn More

Our mission is to end the threat of age-related disease for this and future generations

We believe it is possible for people to enjoy their lives at 95 as much as they do at 25, and to achieve that, we’re seeking a more comprehensive understanding of the biology of aging itself.

Advancing the frontiers
of aging research

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

First actionable clock that predicts immunological health and chronic diseases of aging

Research highlights the critical role of the immune system in the aging process

Aging: It’s more complicated than we thought

Buck researchers make surprising discovery about the connection between protein shape and mitochondrial health

Old Dogs, New Tricks: New Roles for FGF21, a Well-Known Metabolic Molecule

By Melia Granath-Panelo and Enrique Carrera, Dominican University of California Graduate Students Edited by Dr...

“What I want people to know about the Buck is the incredible commitment and excitement that permeates the walls of this institution. We are pushing the frontiers in an area that is going to impact all of humanity. I cannot tell you exactly when this will happen, but I can tell you big discoveries will come out of the Buck.”

Eric Verdin, MD, Buck Institute President and CEO

Unexpected proteome plasticity in response to persistent temperature rise

Study in budding yeast brings molecular biology to climate change

The first non-invasive biomarker to track and verify efficacy of senolytic drugs

The discovery and development of a lipid-metabolite biomarker is expected to facilitate research and clinical trials of drugs that target multiple age-related diseases

Chronic viral infections can have lasting effects on human immunity, similar to aging

Researchers identify signatures of immune dysfunction that are shared in aging and chronic viral infections of HIV and Hepatitis C
View more news

Here’s what’s happening

Upcoming events at the Buck

Service Animal Accommodation

Formal Research Seminars

FRS talks are being held via Zoom by invitation only.

OVA Hour: A monthly webinar series created for OVA members

Buck Job Alert! The Buck Institute is looking for a motivated, hands-on Senior Accountant to join our Finance team. For more info and to apply:

Protein homeostasis goes south with aging. Study in @Cell_Metabolism shows genetic tweak that extends lifespan in 3 model organisms. Some anti-aging drugs had similar effects. Good news for those of us farther up food chain?

Overexpressing the protein NANOG in myoblasts reverses aging of skeletal muscle. Research @UBuffalo could lead to treatments for #atherosclerosis #osteoporosis and other age-related diseases. Study also highlights Irish folklore!

Happy to collaborate with my colleagues @BuckInstitute and for the opportunity to contribute to an interesting review @NatureAging discussing COVID-19 and the aging immune system! Please check it out! I hope you find it helpful! #BuckInstitute #UCLA

Had a great time on stage with @davidasinclair @EricVerdin @jenngarrison at the main stage of @SALTConference @BuckInstitute @LongevityTech @PeterDiamandis - my recommendation is know your numbers! What is your vitamin D, cholesterol and sugar level? #SALTNY

Visit the
Buck Institute

Come and share in the excitement. Our doors are open, and we love talking about our science.

Join the fight against age-related diseases

You don’t have to be a scientist to make an important contribution to research on aging. We rely on donations to support the science that we believe will add years to people’s lifespan and decades to their healthspan.

Learn more