Live better longer.

Working to create a world where everyone can have
healthy minds and healthy bodies at every age.

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A mission-driven community
of investigators

The Buck is a collective of the world’s top scientists in the field of aging who are sharing their methods and
expertise to find ways to help everyone lead fuller, healthier lives by ending age-related disease.

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Advancing the frontiers
of research on aging

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

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Our mission is to end the threat of age-related disease for this and future generations

We believe it is possible for people to enjoy their lives at 95 as much as they do at 25, and to achieve that, we’re seeking a more comprehensive understanding of the biology of aging itself.

Advancing the frontiers
of aging research

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

Astera Institute and Buck Institute announce $70 million collaboration to redefine the field of research on aging

The Rejuvenome Project is a first of its kind study seeking to fully characterize aging and validate optimal longevity intervention combinations for extending lifespan

Buck Institute awarded $14 million from NIH to study cellular senescence and Alzheimer’s

Focusing on one of the major drivers of aging brings a new approach to Alzheimer’s and dementia research

Buck Institute awarded $12.7 million from NIH to join SenNet, Cellular Senescence Network

Buck scientists will identify and characterize senescent cells - recognized as a driver of age-related disease - in human ovaries, breast tissue and skeletal muscle

“What I want people to know about the Buck is the incredible commitment and excitement that permeates the walls of this institution. We are pushing the frontiers in an area that is going to impact all of humanity. I cannot tell you exactly when this will happen, but I can tell you big discoveries will come out of the Buck.”

Eric Verdin, MD, Buck Institute President and CEO

Here’s what’s happening

Upcoming events at the Buck

Service Animal Accommodation
Ongoing

Formal Research Seminars

FRS talks are being held via Zoom by invitation only.

How cellular senescence could help stop the scourge of Alzheimer’s, cancer and other chronic diseases

$27 million in federal grants propels the Buck’s pioneering research in cellular senescence as the NIH looks to research in...

Moving our body changes our brain. More evidence that exercise (even simple #walking) improves brain health in the elderly. Study shows activity reduces pro-inflammatory microglial states in humans. https://www.jneurosci.org/content/early/2021/11/11/JNEUROSCI.1483-21.2021 #brainhealth

Human heart muscle cells don’t multiply after birth, but scientists @HopkinsMedicine have new evidence in mice that manipulating certain nerve cells might trigger formation of new muscle; a promising discovery for restoring function after #heartattacks. https://www.eurekalert.org/news-releases/936225

@SAngeli_PhD research @BuckInstitute "Determine if use of the widely-prescribed drug cyclosporin A slows the progression of brain aging"

https://gitcoin.co/grants/3935/determine-if-use-of-the-widely-prescribed-drug-cy

That cup of joe might be more helpful than you think. Researchers @uwaterloo found that #caffeine increases reactions to moving targets. Think safer bike rides, street crossings, even avoiding cart crashes while grocery shopping! https://www.eurekalert.org/news-releases/936436

Join us for Buck webinar on Dec 9: Could taming cellular #senescence help stop the scourge of #Alzheimers, #cancer and other chronic diseases? Buck was recently awarded $27 Million to find out! Hear from 3 Buck scientists on our discovery process. https://www.buckinstitute.org/events/27-million-in-federal-grants-propels-the-bucks-pioneering-research-in-cellular-senescence-as-the-nih-looks-to-research-in-aging-to-stop-the-scourge-of-alzheimers-and-other-chronic-d/

Visit the
Buck Institute

Come and share in the excitement. Our doors are open, and we love talking about our science.

Join the fight against age-related diseases

You don’t have to be a scientist to make an important contribution to research on aging. We rely on donations to support the science that we believe will add years to people’s lifespan and decades to their healthspan.

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