Live better longer.

Working to create a world where everyone can have
healthy minds and healthy bodies at every age.

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A mission-driven community
of investigators

The Buck is a collective of the world’s top scientists in the field of aging who are sharing their methods and
expertise to find ways to help everyone lead fuller, healthier lives by ending age-related disease.

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Advancing the frontiers
of research on aging

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

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Our mission is to end the threat of age-related disease for this and future generations

We believe it is possible for people to enjoy their lives at 95 as much as they do at 25, and to achieve that, we’re seeking a more comprehensive understanding of the biology of aging itself.

Advancing the frontiers
of aging research

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

New findings for the function of tau in neurodegenerative disease

Cutting-edge proteomics enables the mapping of the “tau interactome”

Astera Institute and Buck Institute announce $70 million collaboration to redefine the field of research on aging

The Rejuvenome Project is a first of its kind study seeking to fully characterize aging and validate optimal longevity intervention combinations for extending lifespan

The promise of Metformin highlights the need for precision medicine

Metformin became a “darling” of research on aging when medical records revealed that people with diabetes taking the drug often lived longer, healthier lives.

“What I want people to know about the Buck is the incredible commitment and excitement that permeates the walls of this institution. We are pushing the frontiers in an area that is going to impact all of humanity. I cannot tell you exactly when this will happen, but I can tell you big discoveries will come out of the Buck.”

Eric Verdin, MD, Buck Institute President and CEO

Forever Healthy and the Buck Institute Announce Partnership to Advance Translational Research in Human Rejuvenation

Michael Greve's Forever Healthy Foundation commits $5 million to fund breakthrough science with strong potential for startup creation at the Buck.

Buck Institute awarded $12.7 million from NIH to join SenNet, Cellular Senescence Network

Buck scientists will identify and characterize senescent cells - recognized as a driver of age-related disease - in human ovaries, breast tissue and skeletal muscle

Four Buck professors recognized as among most highly cited researchers in the world

Listing is based on the publication of multiple highly cited research papers.
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Here’s what’s happening

Upcoming events at the Buck

Service Animal Accommodation
Ongoing

Formal Research Seminars

FRS talks are being held via Zoom by invitation only.

OVA Hour: A monthly webinar series created for OVA members

Study in @NatureAging identifies two blood proteins that could be the key to a long, healthy life. Both proteins are linked to clotting and heart health. New targets for drug development! https://www.eurekalert.org/news-releases/940950

Destroying #senescent cells in the aging stem cell niche enhances #neurogenesis in the hippocampus and improves cognitive function in mice. Published in @StemCellReports, researchers say dormant stem cells “woke up” after treatment. https://www.eurekalert.org/news-releases/940091

Supplementation of a compound produced in the gut appears to boost muscle and mitochondrial health in humans. Published in @JAMANetworkOpen, urolthin A may improve muscle activity during aging. https://www.eurekalert.org/news-releases/940275

Congrats to the Buck’s Tara Tracy, lead author in today’s study in Cell. There are new findings for the function of #tau in neurodegenerative disease and the introduction of the “tau interactome.” https://zcu.io/barh

Getting enough magnesium? Research shows it’s essential for the #immunesystem and the fight against #cancer. Study in @CellPressNews reveals that T cells need a sufficient quantity of the mineral in order to operate efficiently. https://www.eurekalert.org/news-releases/940025

Visit the
Buck Institute

Come and share in the excitement. Our doors are open, and we love talking about our science.

Join the fight against age-related diseases

You don’t have to be a scientist to make an important contribution to research on aging. We rely on donations to support the science that we believe will add years to people’s lifespan and decades to their healthspan.

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