Live better longer.

Working to create a world where everyone can have
healthy minds and healthy bodies at every age.

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A mission-driven community
of investigators

The Buck is a collective of the world’s top scientists in the field of aging who are sharing their methods and
expertise to find ways to help everyone lead fuller, healthier lives by ending age-related disease.

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Advancing the frontiers
of research on aging

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

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Our mission is to end the threat of age-related disease for this and future generations

We believe it is possible for people to enjoy their lives at 95 as much as they do at 25, and to achieve that, we’re seeking a more comprehensive understanding of the biology of aging itself.

Advancing the frontiers
of aging research

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

A metabolite produced by the body increases lifespan and dramatically compresses late-life morbidity in mice

Alpha-ketaglutarate improves several measures of healthspan in double-blind study

The Buck Institute mourns the passing of Paul F. Glenn

Major champion of research on aging.

Driving that Gene, Mutations are Seen: Spreading a new trait through a viral population

Using a CRISPR-based gene drive as a new tool to combat viruses

“What I want people to know about the Buck is the incredible commitment and excitement that permeates the walls of this institution. We are pushing the frontiers in an area that is going to impact all of humanity. I cannot tell you exactly when this will happen, but I can tell you big discoveries will come out of the Buck.”

Eric Verdin, MD, Buck Institute President and CEO

The Buck is awarded three federal grants to target aging to prevent or cure Alzheimer’s disease.

The Buck is thrilled to announce that we have received nearly $10M in funding from the NIH for a geroscience approach to developing treatments for Alzheimers.

Global Consortium for Reproductive Longevity & Equality Announces First Grant Recipients

22 Researchers Selected to Receive $7.4 million in Grant Funding to Advance the Field of Reproductive Aging

Researchers outline strategy for testing ketone bodies against COVID-19, other respiratory infections

Review in Med highlights the role of geroscience in the fight against this and future pandemics.
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Here’s what’s happening

Upcoming events at the Buck

Service Animal Accommodation
Ongoing

Formal Research Seminars

FRS talks are being held via Zoom through 2020.
Click “read more” for full schedule

A must-read editorial from @VictorDzau, Elizabeth Finkelman , Celynne Balatbat, @EricVerdin, and Roderic Pettigrew in @ScienceTM​ on the need to accelerate #aging science to achieve healthy #longevity worldwide https://stm.sciencemag.org/content/12/566/eabd3816.full

Hot off the Buck blog press! As the world gets a crash course on #virology, Buck scientists have been using #CRISPR technology to make viruses weaker and less infectious. Read the background story from lead scientist Marius Walter here! https://www.buckinstitute.org/blog/driving-that-gene-mutations-are-seen-spreading-a-new-trait-through-a-viral-population/

Feeling stiff with age? So do ovaries! Read new, exciting work by #CRLE Professor #FrancescaDuncan @NUDuncanLab linking #ovarian fibrosis to changes in #collagen and #hyaluron with age. https://onlinelibrary.wiley.com/doi/full/10.1111/acel.13259

Join us next Wed 10/21 for our symposium "Mechanisms of declining protective immunity despite heightened chronic inflammation during aging" Chaired by @DrEmilyGoldberg! Speakers Dawn Bowdish, Mladen Jergovic, Elsa Bou Ghanem, and Dan Winer!

Read a great overview of how #COVID19 challenges the #aging #immunesystem and the possibility of anti-aging drug candidates to boost immune response. @EricVerdin talks #senescence! https://www.nature.com/articles/d41586-020-02856-7

Visit the
Buck Institute

Come and share in the excitement. Our doors are open, and we love talking about our science.

Join the fight against age-related diseases

You don’t have to be a scientist to make an important contribution to research on aging. We rely on donations to support the science that we believe will add years to people’s lifespan and decades to their healthspan.

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