Live better longer.

Working to create a world where everyone can have
healthy minds and healthy bodies at every age.

Learn More

A mission-driven community
of investigators

The Buck is a collective of the world’s top scientists in the field of aging who are sharing their methods and
expertise to find ways to help everyone lead fuller, healthier lives by ending age-related disease.

Learn More

Advancing the frontiers
of research on aging

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

Learn More

Our mission is to end the threat of age-related disease for this and future generations

We believe it is possible for people to enjoy their lives at 95 as much as they do at 25, and to achieve that, we’re seeking a more comprehensive understanding of the biology of aging itself.

Advancing the frontiers
of aging research

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

Buck celebrates 30 years of research on aging with major symposium

Leading scientists from across the nation gathered at the Buck on December 3rd to celebrate research on aging.

MANF identified as a rejuvenating factor in parabiosis

Buck researchers also harness an innate repair mechanism to protect against liver damage in aging mice and extend lifespan in flies...

Running trails or genetic pathways: The future of exercise

What if you could receive the benefits of exercise moving only the muscles necessary to take a pill?

“What I want people to know about the Buck is the incredible commitment and excitement that permeates the walls of this institution. We are pushing the frontiers in an area that is going to impact all of humanity. I cannot tell you exactly when this will happen, but I can tell you big discoveries will come out of the Buck.”

Eric Verdin, MD, Buck Institute President and CEO

Exploiting a gene that protects against Alzheimer’s

Anyone who gets tested for their genetic risk for Alzheimer’s disease likely knows about ApoE4.

Does dietary restriction protect against age-related leaky gut?

Buck Institute research shows that diet impacts the fitness of cells lining the intestinal tract. In flies, dietary restriction prevents leaky gut with aging, and a rich diet promotes it...

Buck researchers get $3.4 million to look at a fruit-derived metabolite as a possible treatment for Alzheimer’s

Could a gut metabolite produced from dietary ellagic acid, which is abundant in strawberries, blackberries, cranberries, pomegranates and walnuts, help prevent or reverse Alzheimer’s disease?
View more news

Here’s what’s happening

Upcoming events that feature Buck science


Formal Research Seminars

Click “read more” for full schedule

Paint the Town Red

Novato's 59th birthday party!

Marc Freedman on How to Live Forever

Buck hosts the Commonwealth Club

Ageless, by Bridgette Dutta Portman

Arts at the Buck – A reading of the speculative-fiction play: Ageless, or A Revolt of the Flesh

Buck adjunct prof and @InSilicoMeds CEO Alex Zhavoronkov (@biogerontology) uses #AI & prediction modeling to show that smoking accelerates biological aging. Predicted ages were 2X higher than actual age in smokers compared to non-smokers. #livebetterlonger

Does #aging necessarily mean slowing down? New research using the worm C. elegans identifies a molecule, SLO-1, associated with decreased motor function during aging. Targeting of SLO-1 enhanced motor activity and #lifespan in aged worms. #livebetterlonger

Thanks for the mention @sciencedaily!
MANF identified as a rejuvenating factor in parabiosis

Buck researchers show MANF is a rejuvenating factor in parabiosis. Publishing in @NatMetabolism, the Jasper lab harnesses the innate repair mechanism to protect against liver damage in aged mice and extend lifespan in flies. #livebetterlonger

We had a great time with the Girl Scouts @GSNorCal this weekend!! We love sharing the Buck with our community and even more when we get to encourage girls in science!! #livebetterlonger

Visit the
Buck Institute

Come and share in the excitement. Our doors are open, and we love talking about our science.

Join the fight against age-related diseases

You don’t have to be a scientist to make an important contribution to research on aging. We rely on donations to support the science that we believe will add years to people’s lifespan and decades to their healthspan.

Learn more