Live better longer.

Working to create a world where everyone can have
healthy minds and healthy bodies at every age.

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A mission-driven community
of investigators

The Buck is a collective of the world’s top scientists in the field of aging who are sharing their methods and
expertise to find ways to help everyone lead fuller, healthier lives by ending age-related disease.

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Advancing the frontiers
of research on aging

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

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Our mission is to end the threat of age-related disease for this and future generations

We believe it is possible for people to enjoy their lives at 95 as much as they do at 25, and to achieve that, we’re seeking a more comprehensive understanding of the biology of aging itself.

Advancing the frontiers
of aging research

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

Buck researchers discover how cellular senescence leads to neurodegeneration

Findings available to scientists studying both dementia and brain cancer.

Stage is set to develop clinically relevant, senescence-based biomarkers of aging

Proteomic Atlas of Senescence-Associated Secretomes can be used by the research community to speed translation of therapeutics to clinical use

Ow-steoporosis: New research directions for a common condition

Read our latest blog post for info on how scientists are looking into ways to build bone health

“What I want people to know about the Buck is the incredible commitment and excitement that permeates the walls of this institution. We are pushing the frontiers in an area that is going to impact all of humanity. I cannot tell you exactly when this will happen, but I can tell you big discoveries will come out of the Buck.”

Eric Verdin, MD, Buck Institute President and CEO

More details on 500% lifespan extension highlight Buck’s role in moving science forward

The dramatic lifespan extension occurred in a worm with mutations in two different cellular pathways known to influence aging and lifespan.

Get to Know the New Chair of our Board of Trustees – In Conversation with Jill Kinney

Jill Kinney likes to live well and move fast. After building one of the most successful fitness club businesses in the world, she was looking for another way of having an impact on health and wellness...

The Bia-Echo Foundation announces the Global Consortium for Female Reproductive Longevity and Equality in partnership with the Buck Institute

The Consortium will award $7.4 million in grants over the next two years to scientists around the world...
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Here’s what’s happening

Upcoming events at the Buck

Service Animal Accommodation
Ongoing

Formal Research Seminars

Click “read more” for full schedule

2020 Design for Aging

The San Francisco Chapter of the American Institute of Architects will explore the built environment.

Bay Area Worm Meeting 2020

Abstract deadline: May 23

Brain Camp

Designed for students ages 10–12 years old

Feast or famine, but maybe not both. New data suggest that drosophila switching from #caloricrestriction to a calorie-rich diet had shorter average lifespan than those who ate a high calorie diet the whole time. #livebetterlonger https://www.eurekalert.org/pub_releases/2020-02/uos-nrc022020.php

You can choose your diet, but can your cardiomyocytes? In mice, switching them back to glucose (like during development) might improve their regenerative capacity and prevent #heartfailure. #livebetterlonger https://www.eurekalert.org/pub_releases/2020-02/usmc-cwh022120.php

We know about exercising to help your brain, but what about the reverse? A new study from Berkeley found that glial cells (neuronal support cells) send long-lasting signals to support muscle cells and increase lifespan in C. elegans #livebetterlonger https://www.eurekalert.org/pub_releases/2020-02/uoc--bcp022120.php

Not only is the microbiome important for #immune regulation, but there are distinct niches with cell-type specific activation. Lots of great new insights from the @humancellatlas and @sangerinstitute #livebetterlonger https://zcu.io/tqO1

Today in sentences you never thought you’d read: IBM (along w/ UCSD) can use your poop to estimate your age. But it’s actually pretty cool! Turns out there are lots of age-predictive changes to the #microbiome #livebetterlonger https://www.sciencedaily.com/releases/2020/02/200211134432.htm

Visit the
Buck Institute

Come and share in the excitement. Our doors are open, and we love talking about our science.

Join the fight against age-related diseases

You don’t have to be a scientist to make an important contribution to research on aging. We rely on donations to support the science that we believe will add years to people’s lifespan and decades to their healthspan.

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