Live better longer.

Working to create a world where everyone can have
healthy minds and healthy bodies at every age.

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A mission-driven community
of investigators

The Buck is a collective of the world’s top scientists in the field of aging who are sharing their methods and
expertise to find ways to help everyone lead fuller, healthier lives by ending age-related disease.

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Advancing the frontiers
of research on aging

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

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Our mission is to end the threat of age-related disease for this and future generations

We believe it is possible for people to enjoy their lives at 95 as much as they do at 25, and to achieve that, we’re seeking a more comprehensive understanding of the biology of aging itself.

Advancing the frontiers
of aging research

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

Astera Institute and Buck Institute announce $70 million collaboration to redefine the field of research on aging

The Rejuvenome Project is a first of its kind study seeking to fully characterize aging and validate optimal longevity intervention combinations for extending lifespan

Forever Healthy and the Buck Institute Announce Partnership to Advance Translational Research in Human Rejuvenation

Michael Greve's Forever Healthy Foundation commits $5 million to fund breakthrough science with strong potential for startup creation at the Buck.

The promise of Metformin highlights the need for precision medicine

Metformin became a “darling” of research on aging when medical records revealed that people with diabetes taking the drug often lived longer, healthier lives.

“What I want people to know about the Buck is the incredible commitment and excitement that permeates the walls of this institution. We are pushing the frontiers in an area that is going to impact all of humanity. I cannot tell you exactly when this will happen, but I can tell you big discoveries will come out of the Buck.”

Eric Verdin, MD, Buck Institute President and CEO

Buck Institute awarded $12.7 million from NIH to join SenNet, Cellular Senescence Network

Buck scientists will identify and characterize senescent cells - recognized as a driver of age-related disease - in human ovaries, breast tissue and skeletal muscle

Four Buck professors recognized as among most highly cited researchers in the world

Listing is based on the publication of multiple highly cited research papers.

First actionable clock that predicts immunological health and chronic diseases of aging

Research highlights the critical role of the immune system in the aging process
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Here’s what’s happening

Upcoming events at the Buck

Service Animal Accommodation
Ongoing

Formal Research Seminars

FRS talks are being held via Zoom by invitation only.

#Exercise in the morning or evening? The timing has different effects in an organ-specific manner – at least in mice. Published in @Cell_Metabolism, researchers offer the Atlas of Exercise Metabolism as a guide for future studies. https://www.eurekalert.org/news-releases/940181

We’re looking forward to hearing our CEO @ericverdin speak at @Columbiamsph's Centennial Events on January 26 @ 4:30pm EST. Virtual Webinar ➡️ Longevity Research and the Clinic: the geroscience hypothesis. Sign up for free at http://www.publichealth.columbia.edu/public-health-now/events/centennial-events

Researchers @IcahnMountSinai analyzed the genetic activity of thousands of human microglia, the brain’s immune cells. Findings @NatureGenet support link between those cells and some cases of #Alzheimers and #Parkinsons. https://www.eurekalert.org/news-releases/938926

Inflammatory markers for #Alzheimers are conspicuous at early stages, based on a study of cerebrospinal fluid from more than 1,000 older adults. Good news from @NeuroCellPress: some of the markers seem to be involved in damage control. https://www.eurekalert.org/news-releases/939916

#Obesity increases the risk for #cancer. Why? Study @NatureComms shows that lipids associated with obesity make cancer cells more aggressive and likely to form tumors. https://www.eurekalert.org/news-releases/939783

Visit the
Buck Institute

Come and share in the excitement. Our doors are open, and we love talking about our science.

Join the fight against age-related diseases

You don’t have to be a scientist to make an important contribution to research on aging. We rely on donations to support the science that we believe will add years to people’s lifespan and decades to their healthspan.

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