Live better longer.

Working to create a world where everyone can have
healthy minds and healthy bodies at every age.

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A mission-driven community
of investigators

The Buck is a collective of the world’s top scientists in the field of aging who are sharing their methods and
expertise to find ways to help everyone lead fuller, healthier lives by ending age-related disease.

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Advancing the frontiers
of research on aging

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

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Our mission is to end the threat of age-related disease for this and future generations

We believe it is possible for people to enjoy their lives at 95 as much as they do at 25, and to achieve that, we’re seeking a more comprehensive understanding of the biology of aging itself.

Advancing the frontiers
of aging research

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

Buck Scientist Uncovers Clues to Aging in Mitochondria

Understanding how the process starts can point to new directions in aging research

A naturally-occurring metabolite is a potent senolytic in both mice and human cell culture

25-hydroxycholesteral shows particular efficacy in skeletal muscle

Buck researchers weigh in on why women are more likely to develop Alzheimer’s disease

A team from China has identified a reproductive hormone that may play a key role in boosting susceptibility for Alzheimer’s in women...

“What I want people to know about the Buck is the incredible commitment and excitement that permeates the walls of this institution. We are pushing the frontiers in an area that is going to impact all of humanity. I cannot tell you exactly when this will happen, but I can tell you big discoveries will come out of the Buck.”

Eric Verdin, MD, Buck Institute President and CEO

Common gene variant in gynecologic disorders suggests new options for screening for heart disease and cancer

What started out as largely an academic endeavor is turning out to impact a lot of women.

New findings for the function of tau in neurodegenerative disease

Cutting-edge proteomics enables the mapping of the “tau interactome”

Astera Institute and Buck Institute announce $70 million collaboration to redefine the field of research on aging

The Rejuvenome Project is a first of its kind study seeking to fully characterize aging and validate optimal longevity intervention combinations for extending lifespan
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Here’s what’s happening

Upcoming events at the Buck

Service Animal Accommodation
Ongoing

Formal Research Seminars

FRS talks are being held via Zoom by invitation only.

Impact Circle 2022

Buck was thrilled to participate again this year at @BayAreaSciFest in Santa Rosa, CA last Sunday as a Hosting Sponsor and exhibitor. We love sharing our science with aspiring young scientists! We had so much fun!!

Snag in normal process of cleaning up broken DNA in brain cells may hasten progression of #Parkinsons. Researchers @HopkinsMedicine found protein “Sting” creates a cycle of inflammation when it responds to clean-up signals in cells already damaged by PD https://www.eurekalert.org/news-releases/953355

Great work from the Zhou lab! Buck researchers have uncovered clues as to how aging starts to happen in #mitochondria, opening a completely different way to think about, measure, mitigate and reverse the process. Study is in @eLife https://www.buckinstitute.org/news/buck-scientist-uncovers-clues-to-aging-in-mitochondria/

1st of “Five Things I’ve Learned About Aging” series kicks off next Tues with a convo with @MilkenInstitute Fellow Paul Irving. As author/editor of The Upside of Aging he’ll talk about new possibilities that are emerging from our longer, healthier lives
https://myfivethings.com/class/paul-irving-the-upside-of-aging/

Another huge congratulations to Dr. Tyler Hilsabeck on receiving his Doctor of Philosophy degree in Biology of Aging from @USCLeonardDavis School of Gerontology. We've watched you work so hard! We're so proud to call you a Buck PhD! #livebetterlonger

Visit the
Buck Institute

Come and share in the excitement. Our doors are open, and we love talking about our science.

Join the fight against age-related diseases

You don’t have to be a scientist to make an important contribution to research on aging. We rely on donations to support the science that we believe will add years to people’s lifespan and decades to their healthspan.

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