Live better longer.

Working to create a world where everyone can have
healthy minds and healthy bodies at every age.

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A mission-driven community
of investigators

The Buck is a collective of the world’s top scientists in the field of aging who are sharing their methods and
expertise to find ways to help everyone lead fuller, healthier lives by ending age-related disease.

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Advancing the frontiers
of research on aging

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

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Our mission is to end the threat of age-related disease for this and future generations

We believe it is possible for people to enjoy their lives at 95 as much as they do at 25, and to achieve that, we’re seeking a more comprehensive understanding of the biology of aging itself.

Advancing the frontiers
of aging research

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

First actionable clock that predicts immunological health and chronic diseases of aging

Research highlights the critical role of the immune system in the aging process

Unexpected proteome plasticity in response to persistent temperature rise

Study in budding yeast brings molecular biology to climate change

Mitochondrial Ubiquinol Oxidation: Could this be the answer to stop tumor growth in its path?

Understanding the role mitochondrial metabolism in tumor growth.

“What I want people to know about the Buck is the incredible commitment and excitement that permeates the walls of this institution. We are pushing the frontiers in an area that is going to impact all of humanity. I cannot tell you exactly when this will happen, but I can tell you big discoveries will come out of the Buck.”

Eric Verdin, MD, Buck Institute President and CEO

The first non-invasive biomarker to track and verify efficacy of senolytic drugs

The discovery and development of a lipid-metabolite biomarker is expected to facilitate research and clinical trials of drugs that target multiple age-related diseases

Chronic viral infections can have lasting effects on human immunity, similar to aging

Researchers identify signatures of immune dysfunction that are shared in aging and chronic viral infections of HIV and Hepatitis C

Studying Alzheimer’s disease in fruit flies? You bet!

A recent $533,000 federal grant to the Buck Institute supports basic research to identify targets for new therapeutics based on how diet and aging influence Alzheimer’s and other neurodegenerative diseases...
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Here’s what’s happening

Upcoming events at the Buck

Service Animal Accommodation

Formal Research Seminars

FRS talks are being held via Zoom by invitation only.

Clear + Vivid + Alan Alda + Cynthia Kenyon. Dr. Kenyon has been at the forefront of the aging biology since the very beginning! @alda #clearandvivid

Register for this deeper dive into #aging and #cancer hosted by the the Oklahoma @NathanShockCtrs and @OUHealth Stephenson Cancer Center. The Buck's Judy Campisi is one of the presenters!

All summer we've been mailing out kits for kids to do science with us! Our August kit is a build-your-own microscope from @TeamFoldscope. These kits are free thanks to a generous grant from the Winnifred Johnson Clive Foundation. Sign up at the link!

Buck Job Alert! The Melov lab at the Buck Institute is looking for a highly motivated in vivo Research Associate II or Scientist to help drive a project focused on the use of simple and complex mouse models. Learn more and apply here:

#NatMetabPicks | Publishing in @Nature, a group led by Heinrich Jasper (@BuckInstitute) uncovers glial metabolic reprogramming by gut-derived cytokines, resulting in changes in the perception of olfaction.

Visit the
Buck Institute

Come and share in the excitement. Our doors are open, and we love talking about our science.

Join the fight against age-related diseases

You don’t have to be a scientist to make an important contribution to research on aging. We rely on donations to support the science that we believe will add years to people’s lifespan and decades to their healthspan.

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