Live better longer.

Working to create a world where everyone can have
healthy minds and healthy bodies at every age.

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A mission-driven community
of investigators

The Buck is a collective of the world’s top scientists in the field of aging who are sharing their methods and
expertise to find ways to help everyone lead fuller, healthier lives by ending age-related disease.

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Advancing the frontiers
of research on aging

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

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Our mission is to end the threat of age-related disease for this and future generations

We believe it is possible for people to enjoy their lives at 95 as much as they do at 25, and to achieve that, we’re seeking a more comprehensive understanding of the biology of aging itself.

Advancing the frontiers
of aging research

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

Does dietary restriction protect against age-related leaky gut?

Buck Institute research shows that diet impacts the fitness of cells lining the intestinal tract. In flies, dietary restriction prevents leaky gut with aging, and a rich diet promotes it...

A new method furthers understanding of evolutionary genetics

Publishing in Nature Genetics, discovery helps unravel the mystery of ancient traits

Buck researchers get $3.4 million to look at a fruit-derived metabolite as a possible treatment for Alzheimer’s

“What I want people to know about the Buck is the incredible commitment and excitement that permeates the walls of this institution. We are pushing the frontiers in an area that is going to impact all of humanity. I cannot tell you exactly when this will happen, but I can tell you big discoveries will come out of the Buck.”

Eric Verdin, MD, Buck Institute President and CEO

World’s first Center for Female Reproductive Longevity and Equality established at the Buck Institute for Research on Aging

A $6 million gift provides seed money to address a long-standing inequality: men can reproduce throughout their lifespan; but women's fertility begins to decline in their early 30's...

Tara Tracy joins faculty at Buck Institute

Neuroscientist studies synaptic dysfunction and cognitive decline in Alzheimer’s

First patient treated with drug based on Buck research

Unity Biotechnology, which incubated at the Buck Institute, has treated the first patient in a Phase I clinical trial evaluating a drug to selectively eliminate senescent cells in moderate to severe osteoarthritis of the knee...
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Here’s what’s happening

Upcoming events that feature Buck science


Formal Research Seminars

Click “read more” for full schedule

Thinking Structure

New Works by: Kirk Stoller, Linda Geary, Sabine Reckewell, Ann-Marie Stöhr, Andy Vogt, Ulrike Palmbach

Live Better Longer: A Celebration of 30 Years in Aging Research

Speakers: 20 thought leaders in aging research

Great talk today from Dr. Hideyuki Okano at @Keio_Univ who is modeling neurological disorders like #ALS using human induced pluripotent stem cells to identify drug candidates, since mouse models don't always recapitulate human disease. #livebetterlonger

Using newly-discovered inhibitors, Buck research shows for the 1st time that mitochondria produce ~50% of hydrogen peroxide in muscle cells. These inhibitors are starting points for drugs to prevent oxidative damage & age-related disease. #livebetterlonger

Research in @GenesDev links a genetic mutation associated with dementia and ALS to altered nutrient-stress response and lipid metabolism. Another reason we are so focused on how basic biological processes affect aging and chronic disease! #livebetterlonger

That's a wrap, everyone! Thank you to those who followed us and #BAAM18 hashtag today.

If you enjoyed today's meeting and would like to hear more about #aging research and perspectives, sign up for this event at The Buck on 12/3:


.@wysscoray points out that as more drugs that combats #aging are developed, they will need to be regulated so there is no huge disparity in access and not only a few benefit from the medicine.

#BAAM18 #livebetterlonger

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Buck Institute

Come and share in the excitement. Our doors are open, and we love talking about our science.

Join the fight against age-related diseases

You don’t have to be a scientist to make an important contribution to research on aging. We rely on donations to support the science that we believe will add years to people’s lifespan and decades to their healthspan.

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