Live better longer.

Working to create a world where everyone can have
healthy minds and healthy bodies at every age.

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A mission-driven community
of investigators

The Buck is a collective of the world’s top scientists in the field of aging who are sharing their methods and
expertise to find ways to help everyone lead fuller, healthier lives by ending age-related disease.

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Advancing the frontiers
of research on aging

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

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Our mission is to end the threat of age-related disease for this and future generations

We believe it is possible for people to enjoy their lives at 95 as much as they do at 25, and to achieve that, we’re seeking a more comprehensive understanding of the biology of aging itself.

Advancing the frontiers
of aging research

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

The first non-invasive biomarker to track and verify efficacy of senolytic drugs

The discovery and development of a lipid-metabolite biomarker is expected to facilitate research and clinical trials of drugs that target multiple age-related diseases

Chronic viral infections can have lasting effects on human immunity, similar to aging

Researchers identify signatures of immune dysfunction that are shared in aging and chronic viral infections of HIV and Hepatitis C

A Shot Towards Ending a Pandemic: Vaccines Explained

In our final blog from our Dominican students, get science-based answers to common vaccine questions...

“What I want people to know about the Buck is the incredible commitment and excitement that permeates the walls of this institution. We are pushing the frontiers in an area that is going to impact all of humanity. I cannot tell you exactly when this will happen, but I can tell you big discoveries will come out of the Buck.”

Eric Verdin, MD, Buck Institute President and CEO

A new predictive model helps identify those at risk for severe COVID-19

Buck scientists analyze data from 3 million people using a smartphone app in the United Kingdom

A compound that slows bone loss, and a resource for developing treatments to slow aging

Longitudinal and functional study of 700 aging mice provides a treasure trove of data for those studying aging and age-related diseases

Tissue stiffness likely drives immune responses in many chronic diseases

Buck research points to the possibility of new immunotherapeutics and highlights critically needed changes in experimental techniques
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Here’s what’s happening

Upcoming events at the Buck

Service Animal Accommodation

Formal Research Seminars

FRS talks are being held via Zoom by invitation only.

Lifelong learning contributes to healthy aging!

6 week course on the Biology of Aging for a non-scientific audience

The Unspoken Truth Webinar

First in a series of webinars devoted to the field of women’s health.

@TheDrWiley discusses cexciting new research he led on cellular #senescence while at @BuckInstitute h

Hot off the Buck blog press: With COVID vaccines being widely available to the public, many are wondering how they work. Our @DominicanCAnews students explain different types and how scientific community was able to develop safe vaccines so quickly.

Quick! You have 9 minutes to get inspired about science and learn why #Celegans is an excellent model organism, especially for #aging and disease. Don't worry, @BBC Witness History and our own Gordon Lithgow gotchu.

Buck Job Alert! Principal Grants & Contracts Analyst w/ research admin experience working w/ faculty in academic or research setting. Ideal candidate has experience w/ various funding types and human subjects research protections and IRB regulations.

New from @KECKSchool_USC: rapid biological aging of #neuralstemcells--they become quiescent and decline as mice reach middle age. Inhibiting the #Abl1 gene in mice led to proliferation of these "long-term" NSCs.

Visit the
Buck Institute

Come and share in the excitement. Our doors are open, and we love talking about our science.

Join the fight against age-related diseases

You don’t have to be a scientist to make an important contribution to research on aging. We rely on donations to support the science that we believe will add years to people’s lifespan and decades to their healthspan.

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