Live better longer.

Working to create a world where everyone can have
healthy minds and healthy bodies at every age.

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A mission-driven community
of investigators

The Buck is a collective of the world’s top scientists in the field of aging who are sharing their methods and
expertise to find ways to help everyone lead fuller, healthier lives by ending age-related disease.

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Advancing the frontiers
of research on aging

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

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Check out our
new podcast!

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Our mission is to end the threat of age-related disease for this and future generations

We believe it is possible for people to enjoy their lives at 95 as much as they do at 25, and to achieve that, we’re seeking a more comprehensive understanding of the biology of aging itself.

Advancing the frontiers
of aging research

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

Brain aging is not one-size-fit-all: Chronological age, biological age and gender affect the shrinkage of different brain areas.

"This work breaks open the black box between aging and neurodegeneration”: Buck Institute associate professor David Furman

High Risk/High Reward Grant Funds Development of Smart Drug Delivery System to Treat Multiple Alzheimer’s Pathologies

The Buck’s $2.4 million Transformative Research Award is one of just nine in the nation

The first successful clinical trial for a new Alzheimer’s drug is making big news.

Buck professor Julie Andersen weighs in on the new Alzheimer’s drug lecanemab.

“What I want people to know about the Buck is the incredible commitment and excitement that permeates the walls of this institution. We are pushing the frontiers in an area that is going to impact all of humanity. I cannot tell you exactly when this will happen, but I can tell you big discoveries will come out of the Buck.”

Eric Verdin, MD, Buck Institute President and CEO

Buck researchers uncover intriguing connection between diet, eye health and lifespan

Buck researchers uncover an intriguing connection between diet, eye health and lifespan in Drosophila

Buck Scientists Highlight New Perspective in How Immunity is Fine-Tuned through Mechanics

Introducing a new scientific discipline: Mechanoimmunlogy

Buck Institute scientists uncover a new role for blood-brain barrier in neuron function and damage

Findings open up a potential new avenue for therapies aimed at countering neurodegeneration
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Here’s what’s happening

Upcoming events at the Buck

Service Animal Accommodation
Ongoing

Formal Research Seminars

FRS talks are being held via Zoom by invitation only.

Brain aging is not one-size-fits-all. Congrats to Furman lab for study @PNASNews which breaks open black box between aging & neurodegeneration. Research shows functional brain networks are affected in different ways by aging, gender & blood immune factors https://www.buckinstitute.org/news/brain-aging-is-not-one-size-fit-all-chronological-age-biological-age-and-gender-affect-the-shrinkage-of-different-brain-areas/

Looking for a great weekend read? Check out the U.S. National Academy of Medicine’s Global Roadmap to Seize the Opportunity of Healthy Longevity! (we heartily endorse). https://zcu.io/h2Lq

Gene expression “memory” can last a lifetime – in fruit flies. Study in @NatureAging reveals a novel target for improving late-life health by counteracting some of the early genetic changes that play out as part of normal fruit fly #aging. https://www.eurekalert.org/news-releases/972941

Research in fruit flies reveals how gender determines responses to #rapamycin. Study in @NatureAging found that the anti-aging drug extended lifespan and slowed intestinal pathologies in females by boosting autophagy. Males? Not so much. https://www.eurekalert.org/news-releases/973030

Silent synapses may help the adult brain to form new memories and absorb new info. Study in mice at @MIT, appearing in @Nature shows these immature connections make up about 30 percent of all synapses in the cortex. Let’s hope it holds true in humans! https://www.eurekalert.org/news-releases/972600

Visit the
Buck Institute

Come and share in the excitement. Our doors are open, and we love talking about our science.

Join the fight against age-related diseases

You don’t have to be a scientist to make an important contribution to research on aging. We rely on donations to support the science that we believe will add years to people’s lifespan and decades to their healthspan.

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