Live better longer.

Working to create a world where everyone can have
healthy minds and healthy bodies at every age.

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A mission-driven community
of investigators

The Buck is a collective of the world’s top scientists in the field of aging who are sharing their methods and
expertise to find ways to help everyone lead fuller, healthier lives by ending age-related disease.

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Advancing the frontiers
of research on aging

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

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Our mission is to end the threat of age-related disease for this and future generations

We believe it is possible for people to enjoy their lives at 95 as much as they do at 25, and to achieve that, we’re seeking a more comprehensive understanding of the biology of aging itself.

Advancing the frontiers
of aging research

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

Buck President and CEO Eric Verdin Appointed to President’s Advisory Council for the Health Longevity Grand Challenge

The National Academy of Medicine is launching a Global Grand Challenge for Healthy Longevity – a worldwide movement to increase physical, mental, and social well-being for people as they age...

Intervening in glial cells protects neurons in Parkinson’s model

Buck researchers identify crosstalk between dopaminergic neurons and glial cells in fruit flies providing a potential new target for preventative treatment.

Running trails or genetic pathways: The future of exercise

What if you could receive the benefits of exercise moving only the muscles necessary to take a pill?

“What I want people to know about the Buck is the incredible commitment and excitement that permeates the walls of this institution. We are pushing the frontiers in an area that is going to impact all of humanity. I cannot tell you exactly when this will happen, but I can tell you big discoveries will come out of the Buck.”

Eric Verdin, MD, Buck Institute President and CEO

Buck Professor Emeritus David Nicholls elected to the Royal Society

David Nicholls, PhD, FRSE, has been elected to the Royal Society, a self-governing Fellowship made up of the most eminent scientists, engineers and technologists from the United Kingdom and the Commonwealth...

MANF identified as a rejuvenating factor in parabiosis

Buck researchers also harness an innate repair mechanism to protect against liver damage in aging mice and extend lifespan in flies...

Exploiting a gene that protects against Alzheimer’s

Anyone who gets tested for their genetic risk for Alzheimer’s disease likely knows about ApoE4.
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Here’s what’s happening

Upcoming events that feature Buck science

Ongoing

Formal Research Seminars

Click “read more” for full schedule
Ongoing

The Conversation Continues: A Celebration of 30 Years of Research on Aging

Leaders in the field discuss the latest in research on aging.

The Buck goes to the movies: Evil Scientists and Hollywood!

Buck celebrates 20 years with this fun, entertaining event!
Ongoing

The Conversation Continues: A Celebration of 30 Years of Research on Aging

Leaders in the field discuss the latest in research on aging.

Free, fun event at the @BuckInstitute on May 9th! The Buck goes to the movies! Professor Simon Melov will host a lighthearted overview of how Hollywood has treated science, specifically the issue of lifespan extension & “evil scientists”. Register! https://t.co/ZjzLn62Exu

#Inflammaging can be driven by the NLRP3 inflammasome in damaged #mitochondria. A study from @UCSDMedSchool that inhibited Choline K led to increased mitophagy and decreased #inflammation in mice #livebetterlonger https://t.co/lgAv5mPm32 #livebetterlonger

That was fast! The free video archive of yesterday's session with George Martin MD, Professor, University of Washington, is now available. #livebetterhttps://buck.extendedsession.com/session/part-two-thirty-years-of-the-genetics-of-aging/ See you at Session 3 on Tues, April 30!

The Buck’s David Nicholls is elected to the Royal Society! Congrats to a pioneer and icon in the field of bioenergetics.
https://t.co/z7XObpUCra

Sweet news! Added #sugar, which makes up >15% of the average American diet, is fuel for many chronic diseases. New labeling and awareness can delay or prevent millions of cases of #diabetes + #cardiovasculardisease #livebetterlonger https://t.co/YkFxID7PcE

Visit the
Buck Institute

Come and share in the excitement. Our doors are open, and we love talking about our science.

Join the fight against age-related diseases

You don’t have to be a scientist to make an important contribution to research on aging. We rely on donations to support the science that we believe will add years to people’s lifespan and decades to their healthspan.

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