Live better longer.

Working to create a world where everyone can have
healthy minds and healthy bodies at every age.

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A mission-driven community
of investigators

The Buck is a collective of the world’s top scientists in the field of aging who are sharing their methods and
expertise to find ways to help everyone lead fuller, healthier lives by ending age-related disease.

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Advancing the frontiers
of research on aging

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

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Our mission is to end the threat of age-related disease for this and future generations

We believe it is possible for people to enjoy their lives at 95 as much as they do at 25, and to achieve that, we’re seeking a more comprehensive understanding of the biology of aging itself.

Advancing the frontiers
of aging research

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

Buck researchers get $3.4 million to look at a fruit-derived metabolite as a possible treatment for Alzheimer’s

Could a gut metabolite produced from dietary ellagic acid, which is abundant in strawberries, blackberries, cranberries, pomegranates and walnuts, help prevent or reverse Alzheimer’s disease?

A new method furthers understanding of evolutionary genetics

Publishing in Nature Genetics, discovery helps unravel the mystery of ancient traits

Advanced Glycation End Products As Drivers of Age-Related Disease

“What I want people to know about the Buck is the incredible commitment and excitement that permeates the walls of this institution. We are pushing the frontiers in an area that is going to impact all of humanity. I cannot tell you exactly when this will happen, but I can tell you big discoveries will come out of the Buck.”

Eric Verdin, MD, Buck Institute President and CEO

Tara Tracy joins faculty at Buck Institute

Neuroscientist studies synaptic dysfunction and cognitive decline in Alzheimer’s

First patient treated with drug based on Buck research

Unity Biotechnology, which incubated at the Buck Institute, has treated the first patient in a Phase I clinical trial evaluating a drug to selectively eliminate senescent cells in moderate to severe osteoarthritis of the knee...

Geriatrician-scientist John Newman, MD, PhD, joins the Buck faculty

Geriatrician and researcher in the field of aging poised to bridge gap between lab and clinical practice.
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Here’s what’s happening

Upcoming events that feature Buck science

Ongoing

Formal Research Seminars

Click “read more” for full schedule

Thinking Structure

New Works by: Kirk Stoller, Linda Geary, Sabine Reckewell, Ann-Marie Stöhr, Andy Vogt, Ulrike Palmbach

North Bay Science Discovery Day

100 hands-on experiences for kids and kids at heart!

Bay Area Aging Meeting (BAAM)

Industry event

Want to regenerate muscle? Just add immune cells. New study published in @NatBME shows #macrophages promote muscle repair and function following injury in 3D engineered tissue culture. Great implications for the treatment of degenerative muscle diseases! https://t.co/dM34RCF9J1

Study in @NatureGenet mapping the whole transcriptome of the aging brain finds aberrant mRNA splicing is a feature of #Alzheimer’s disease. This research may help identify new #biomarkers and treatments for neurodegenerative disease. https://t.co/F6Jr3kgaih

Can #AI help us catch Alzheimer’s before it progresses? Using data from the #Alzheimer’s Disease Neuroimaging Initiative, scientists have designed an algorithm that can predict cognitive decline and may drive preventative treatments. #livebetterlonger https://t.co/nLwrUhTd0F

How are companies using the basic #aging discoveries of Buck scientists to develop new therapies? The @Guardian discusses cellular senescence pioneered by our own Judith Campisi and the startups trying to target it. @UnityBiotech #livebetterlonger https://t.co/GChlLfrQm1

New study in @Cell_Metabolism reveals a previously unknown connection between a central component of the immune system, complement C3, and autophagy in pancreatic beta cells. #livebetterlonger https://t.co/KQ3JAl4X6N

Visit the
Buck Institute

Come and share in the excitement. Our doors are open, and we love talking about our science.

Join the fight against age-related diseases

You don’t have to be a scientist to make an important contribution to research on aging. We rely on donations to support the science that we believe will add years to people’s lifespan and decades to their healthspan.

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