Live better longer.

Working to create a world where everyone can have
healthy minds and healthy bodies at every age.

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A mission-driven community
of investigators

The Buck is a collective of the world’s top scientists in the field of aging who are sharing their methods and
expertise to find ways to help everyone lead fuller, healthier lives by ending age-related disease.

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Advancing the frontiers
of research on aging

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

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Our mission is to end the threat of age-related disease for this and future generations

We believe it is possible for people to enjoy their lives at 95 as much as they do at 25, and to achieve that, we’re seeking a more comprehensive understanding of the biology of aging itself.

Advancing the frontiers
of aging research

Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.

Buck researchers provide a framework to study precision nutrigeroscience

In calling for a personalized approach to diet, a new research sub-specialty deals with the fact that health benefits from many forms of dietary restriction vary and are not “one size fits all”

First actionable clock that predicts immunological health and chronic diseases of aging

Research highlights the critical role of the immune system in the aging process

Old Dogs, New Tricks: New Roles for FGF21, a Well-Known Metabolic Molecule

By Melia Granath-Panelo and Enrique Carrera, Dominican University of California Graduate Students Edited by Dr...

“What I want people to know about the Buck is the incredible commitment and excitement that permeates the walls of this institution. We are pushing the frontiers in an area that is going to impact all of humanity. I cannot tell you exactly when this will happen, but I can tell you big discoveries will come out of the Buck.”

Eric Verdin, MD, Buck Institute President and CEO

Aging: It’s more complicated than we thought

Buck researchers make surprising discovery about the connection between protein shape and mitochondrial health

Unexpected proteome plasticity in response to persistent temperature rise

Study in budding yeast brings molecular biology to climate change

The first non-invasive biomarker to track and verify efficacy of senolytic drugs

The discovery and development of a lipid-metabolite biomarker is expected to facilitate research and clinical trials of drugs that target multiple age-related diseases
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Here’s what’s happening

Upcoming events at the Buck

Service Animal Accommodation
Ongoing

Formal Research Seminars

FRS talks are being held via Zoom by invitation only.

OVA Hour: A monthly webinar series created for OVA members

#Intermittent fasting gets a 👍🏼 as a powerful strategy to prevent and manage diabetes and heart disease. @EndoSocJournals, researchers explore the science, recent clinical studies and plans for future research.  https://www.eurekalert.org/news-releases/928954

The tiny nematode #Celegans can listen through their skin! This workhorse of research on aging continues to amaze us. Research from @umich is published in @neurocellpress https://www.eurekalert.org/news-releases/928925

Given that health benefits from dietary restriction are not “one size fits all,” Buck researchers pitch a new sub-specialty: precision nutrigeroscience. The detailed primer in @cell_metabolism is a must read for those interested in aging and nutrition. https://www.buckinstitute.org/news/buck-researchers-provide-a-framework-to-study-precision-nutrigeroscience/

Great primer with a forward by our own @jenngarrison on ovarian aging and women’s health. Check it out @LongevityTech

Can eating less fat stave off hair loss? A study in aging mice in @nature found that #obesity can lead to depletion of hair follicle stem cells, thanks to certain inflammatory signals which block follicle regeneration. https://www.eurekalert.org/news-releases/929028

Visit the
Buck Institute

Come and share in the excitement. Our doors are open, and we love talking about our science.

Join the fight against age-related diseases

You don’t have to be a scientist to make an important contribution to research on aging. We rely on donations to support the science that we believe will add years to people’s lifespan and decades to their healthspan.

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