NEWS

From the bench to the boardroom

News from the Buck and beyond

news . Dec 05, 2018

Buck celebrates 30 years of research on aging with major symposium

Leading scientists from across the nation gathered at the Buck on December 3rd to celebrate research on aging.

news . Nov 15, 2018

A small foundation has a huge impact on Buck educational programs

Established in 2015, the Navigage Foundation is just getting its feet wet when it comes to supporting efforts to enhance and improve the lives of older adults...

Press Release . Nov 06, 2018

Does dietary restriction protect against age-related leaky gut?

Buck Institute research shows that diet impacts the fitness of cells lining the intestinal tract...

news . Oct 16, 2018

Buck researchers get $3.4 million to look at a fruit-derived metabolite as a possible treatment for Alzheimer’s

Could a gut metabolite produced from dietary ellagic acid, which is abundant in strawberries, blackberries, cranberries, pomegranates and walnuts, help prevent or reverse Alzheimer’s disease?

Press Release . Oct 08, 2018

A new method to pinpoint genetic differences between species

Publishing in Nature Genetics, research from the Buck Institute lays the groundwork for the mapping of genes to traits throughout the plant and animal kingdoms...

What I want people to know about the Buck is the incredible commitment and excitement that permeates the walls of this institution. We are pushing the frontiers in an area that is going to impact all of humanity. I cannot tell you exactly when this will happen, but I can tell you big discoveries will come out of the Buck.

Eric Verdin, MD, Buck Institute President and CEO

news . Jul 29, 2015

Surprising results in study of mitochondrial dysfunction in skin casts light on the free radical theory of aging

Scientists in the Campisi lab at the Buck Institute bred mice that produced excess free radicals that damaged the mitochondria in their skin

news . Jul 28, 2015

An imbalance of cellular bioenergetics in pancreatic beta-cells is linked to type 2 diabetes

Impaired activation of mitochondrial energy metabolism in the presence of glucose has been demonstrated in pancreatic beta-cells from patients with type 2 diabetes...

news . Jul 24, 2015

Low-dose lithium reduces side effects from most common treatment for Parkinson’s disease

Buck Institute research provides further validation that low-dose lithium could be repurposed as a therapy for the incurable neurodegenerative disorder

news . Jun 20, 2015

New paradigm for treating “inflammaging” and cancer

Intermittent dosing with rapamycin breaks inflammatory loop that fuels tumor relapse and age-related diseases

news . Jun 04, 2015

Serotonin receptor is involved in eczema and other itch conditions

Dermatologists have long known that available treatments for chronic itch, including eczema, are simply not up to scratch...

news . May 25, 2015

Complex signaling between blood and stem cells controls regeneration in fly gut

Buck Institute scientists say impaired interactions between macrophages and stem cells are likely players in human intestinal maladies like IBS, leaky gut and colorectal cancers

news . Apr 28, 2015

Calico enters into agreement with the Buck Institute to conduct research into the biology of aging and to identify potential therapeutics for age-related diseases

Calico, a company focused on aging research and therapeutics, and the Buck Institute for Research on Aging have partnered to support research into longevity and age-related diseases...

news . Feb 09, 2015

Mechanistic finding may provide a means to deal with side effects of lifespan-extending drug rapamycin

Rapamycin, an FDA-approved drug, extends lifespan in mice up to 30%

news . Jan 21, 2015

Buck Institute faculty Judith Campisi receives first Olav Thon Foundation Prize

Norway’s largest charitable foundation bestows cash prize for Campisi’s pioneering work on cancer and aging

news . Jan 15, 2015

Is there a connection between heavy metals and aging?

Study in C...

news . Dec 16, 2014

Low-dose lithium prevents Parkinson’s symptoms in aged mice with a human mutation for the disease

Study provides further validation that lithium could be repurposed as a therapy for the incurable neurodegenerative disorder

news . Dec 14, 2014

Senescent cells play an essential role in wound healing

Study highlights ability to avoid a potential side effect of healthspan extending drugs

news . Dec 11, 2014

Could ibuprofen be an anti-aging medicine?

Study shows popular over-the counter drug extends lifespan in yeast, worms and flies

news . Nov 15, 2014

Buck Faculty Henri Jasper, PhD, Receives Prestigious BIG Award

Buck faculty Henri Jasper, PhD, gets prestigious “Breakthroughs in Gerontology” award from the Glenn Foundation and the American Federation for Aging Research

news . Nov 06, 2014

Leading scientists identify research strategy for highly intertwined “pillars of aging”

Leading scientists identify research strategy for highly intertwined “pillars of aging” as next step in supporting the trans-NIH Geroscience Interest Group’s efforts to integrate aging into research on chronic diseases

news . Sep 29, 2014

Memory loss associated with Alzheimer’s reversed for first time

In a novel, personalized and comprehensive program to reverse memory loss, nine of 10 participants displayed subjective or objective improvement in their memories

news . Aug 07, 2014

Researchers propose “disruptive” new system to reclassify tumors

Largest cancer genomic study proposes “disruptive” new system to reclassify tumors

news . Mar 06, 2014

Rachel Brem, PhD, Joins Buck Institute Faculty

Associate Professor studies naturally-occurring genetic variations that impact characteristics of aging

news . Mar 04, 2014

Buck Institute Mourns Death of Catherine Munson, Long-Time Trustee and former Board Chair

Iconic Realtor was Community Activist and Philanthropist

news . Feb 26, 2014

New at the Buck: Huntington disease protein network

Researchers at the Buck Institute have identified and categorized thousands of protein interactions involving huntingtin, the protein responsible for Huntington’s disease (HD)...

news . Feb 18, 2014

Buck faculty Jennifer Garrison, PhD, Named 2014 Sloan Research Fellow by the Alfred P. Sloan Foundation

Buck Assistant Professor Jennifer Garrison, PhD, has been awarded a prestigious Sloan Research Fellowship

news . Jan 09, 2014

Altering Community of Gut Bacteria Promotes Health and Increases Lifespan

Study provides first systemic understanding of aging gut

news . Dec 12, 2013

Five-Fold Lifespan Extension in C. Elegans by Combining Mutants

Research Highlights Possibility of Combination Therapy for Aging

news . Dec 09, 2013

SIRT5 Regulation Has Dramatic Effect on Mitochondrial Metabolism

New study adds to existing resource that identifies targets for SIRT3

news . Nov 20, 2013

Aging Impacts Epigenome in Human Skeletal Muscle

Buck Institute research involves first genome-wide DNA methylation study in disease-free tissue

news . Nov 20, 2013

The Buck Institute for Research on Aging and the University of Southern California Launch the Nation’s First PhD Program in the Biology of Aging

Program is a Landmark in the History of the Buck

news . Oct 21, 2013

Major Alzheimer’s Risk Factor Linked to Red Wine Target

Buck Institute study provides insight for new therapeutics that target the interaction between ApoE4 and a Sirtuin protein

news . Oct 14, 2013

Research in Aging Fruit Flies May Explain the Roots of Metabolic Dysfunction in Aging Humans

Findings provide a rationale for "Why We Just Can’t Eat What We Used To"

news . Sep 10, 2013

Buck Institute Adds Two New Faculty

Their research focuses on very different realms of the nervous system

news . Jun 26, 2013

Research in Fruit Flies Provides New Insight into Barrett’s Esophagus

A new study suggests a change in stem cell function causes cells in lower esophagus to transform into stomach-like cells

news . Jun 17, 2013

Buck Faculty Receives Prestigious Tenovus Award

Buck faculty Gordon Lithgow, PhD, has received the prestigious 2013 Tenovus-Scotland Medal

news . Jun 10, 2013

Lifespan-Extending Drug Given Late in Life Reverses Age-Related Heart Disease in Mice

Rapamycin is already FDA approved for other indications

news . Apr 21, 2013

CDI Partners with Buck to Derive and Bank iPSCs

Cellular Dynamics International Opens Facility in California, Leasing Space from the Buck Institute to Derive and Bank Human Induced Pluripotent Stem Cells

news . Nov 29, 2012

Buck Scientists Publish Genome-Scale Study Identifying Hundreds of Potential Drug Targets for Huntington’s Disease

Scientists searching for ways to develop treatments for Huntington’s disease (HD) just got a roadmap that could dramatically speed their discovery process

news . Nov 01, 2012

Arthur and Drue Gensler Donate $5 Million to Buck Institute

Gift from Board Member and Architectural Visionary Will be Honored by the Naming of Administrative Building

news . Oct 25, 2012

Buck Institute Announces its Founding Partnership with Delos Pharmaceuticals

New Company is Developing Therapeutics for Age-Associated Disease

news . Sep 22, 2012

Buck Institute and UC Santa Cruz Collaborators Make Significant Contribution to Landmark Breast Cancer Study

TCGA study demonstrates existence of four main classes of breast cancer; Buck collaboration points to similarities between a type of breast and ovarian cancer

news . Sep 06, 2012

Stem Cell Agency Awards Buck Faculty $1.5 Million to Make 3-D Model of the Retina

Efforts to understand and treat degenerative eye diseases utilizing stem cell technology just got a boost

news . Jul 25, 2012

Physical Activity Needed In Order To Reap Benefits Of Dietary Restriction

FDA-approved drug improves cardiac and skeletal muscle function and extends lifespan

news . Jul 02, 2012

Physical Activity Needed In Order To Reap Benefits Of Dietary Restriction

Research in flies points to enhanced fatty acid metabolism in muscle as a key driver of the lifespan extending process

news . Jun 28, 2012

Buck Scientists Correct Huntington’s Disease Mutation in Induced Pluripotent Stem Cells

Researchers at the Buck Institute have corrected the genetic mutation responsible for Huntington’s disease (HD) using a human induced pluripotent stem cell

news . Jun 15, 2012

Glenn Foundation Awards Buck Institute $1 Million to Establish Training Fellowships in the Biology of Aging

The monies will bring new postdoctoral fellows to the Buck Institute, funding two years of research for each of 10 scientists

news . May 21, 2012

Modifying Scar Tissue Can Potentially Improve Outcome in Chronic Stroke

Buck Institute animal study builds on spinal cord injury research

news . Apr 12, 2012

New Regenerative Medicine Research Center to Open at Buck Institute

Public Invited to April 14 Open House/Ribbon Cutting

news . Mar 28, 2012

Buck Institute Helps Launch National “Healthspan Campaign”

Press Event in Washington, DC is hosted by Alliance for Aging Research

news . Jan 31, 2012

Need an Excuse to Book a Massage? Research Shows it Reduces Inflammation and Promotes Growth of New Mitochondria Following Strenuous Exercise

Massage reduces inflammation and promotes the growth of new mitochondria in skeletal muscle

news . Dec 20, 2011

Management Consultant, Community Leader James Edgar Elected to Chair Buck Institute Board of Trustees

James M. Edgar, a life-long management consultant and community leader has been elected Chair of the Board of Trustees

news . Sep 27, 2011

Buck Institute Adds Two New Faculty

Stem cell technologies will be utilized to study vision disorders and skeletal muscle physiology

news . Sep 19, 2011

Scientists Turn Back the Clock on Adult Stem Cells Aging

Reversing the aging process could lead to medical treatments for many chronic conditions

news . Jun 30, 2011

Researchers Flip the Switch Between Aging and Development in C. elegans

Buck Institute scientists note first observation of genome-wide shift kicked off at level of translation that extends lifespan

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blog . Dec 12, 2018

30 years and ongoing: Recap of the 30 years of aging research symposium

Last Monday, roughly 350 people gathered at the Buck to attend the “Live Better Longer: A Celebration of 30 Years of Research on Aging” symposium.

blog . Dec 06, 2018

A perennial molecule that treats pellagra and pauses aging

Recent paper shows a new approach to enhance the body's production of NAD+.

blog . Nov 27, 2018

Giving Tuesday: Why give to the Buck

Why give to the Buck? Hear from some of our amazing donors.

blog . Nov 15, 2018

Longevity: Is it all in the family?

For many of us, our parents have given us a lot...

blog . Nov 13, 2018

Welcome to the inaugural edition of the Live Better Longer blog!

The Buck Institute’s official blog on aging.

Nov 21, 2018

Fountains of youth: Biotech startups emerge from stealth mode to ‘take on aging’

Oct 23, 2018

MIT Technology Review profiles Judy Campisi and her research on cellular senescence

Nov 1, 2018

Buck Institute donor tackles equality through fertility

Dec 4, 2018

Buck Institute in Novato marks 30 years of aging research

Aug 14, 2018

Three leaders in longevity biotechnology form a research collaboration

Here’s what’s happening

Upcoming events that feature Buck science

Ongoing

Formal Research Seminars

Click “read more” for full schedule

JAN 25, 2019

Paint the Town Red

Novato's 59th birthday party!

JAN 30, 2019

Marc Freedman on How to Live Forever

Buck hosts the Commonwealth Club

See all events

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Buck Institute @BuckInstitute·

If you missed last Monday's #30yearsofaging meeting or wanted to relive the discussions, check out today's blog post: https://t.co/NXZGRR4RMU You will also get to hear what some of the attendees thought of the meeting! #livebetterlonger”

Buck Institute @BuckInstitute·

Did you know? The Buck’s regenerative medicine program involves replacing damaged cells, enhancing adult stem cells to rejuvenate tissues and genetically altering deadly mutations. #livebetterlonger #knowthebuck Learn more fun science facts at https://t.co/JTrJ0L5F9F

Buck Institute @BuckInstitute·

Did you know? About 65% of older adults suffer from a chronic disease and 43% have three or more. At the Buck, our research is all about reducing these numbers. #livebetterlonger #30yearsofaging Learn more about aging at https://t.co/JhDVBOMQ8q

Buck Institute @BuckInstitute·

At Friday's FRS, Dr. Claudio Hetz at @uchile discussed his proteostasis work! Maintaining proteostasis (protein + homeostasis) is important for healthy brain aging because it prevents abnormal protein aggregation. Check out our upcoming FRSs: https://t.co/BXRsNfvSmU

Buck Institute @BuckInstitute·

Raising NAD+ levels has been linked to lifespan and #healthspan extension in model organisms. In our latest #livebetterlonger blog post, @DominicanCANews master's student Geoff Meyerhof discusses new research aimed at boosting NAD+ production in vivo. https://t.co/aTXrA5M8lO

NEWS

From the bench to the boardroom

Buck celebrates 30 years of research on aging with major symposium

A small foundation has a huge impact on Buck educational programs

Does dietary restriction protect against age-related leaky gut?

Buck researchers get $3.4 million to look at a fruit-derived metabolite as a possible treatment for Alzheimer’s

A new method to pinpoint genetic differences between species

30 years and ongoing: Recap of the 30 years of aging research symposium

A perennial molecule that treats pellagra and pauses aging

Giving Tuesday: Why give to the Buck

Longevity: Is it all in the family?

Welcome to the inaugural edition of the Live Better Longer blog!

The Search for Mediators of Aging

Bay Area seeing rush of research, investment in human longevity

Bay Area firm at forefront of science seeking arthritis cure

Fountains of youth: Biotech startups emerge from stealth mode to ‘take on aging’

MIT Technology Review profiles Judy Campisi and her research on cellular senescence

Buck Institute donor tackles equality through fertility

Buck Institute in Novato marks 30 years of aging research

Three leaders in longevity biotechnology form a research collaboration

Event Highlights

Here’s what’s happening

Formal Research Seminars

Paint the Town Red

Marc Freedman on How to Live Forever

MEDIA CENTER

Need more information about the Buck?

Keep up with the Buck