RNAi is a phenomenon of gene silencing which offers a quick and easy way to determine the function of a gene. We will use the nematode C. elegans to study this Nobel prize-winning technique that was first identified in C.elegans. It is surprisingly a simple experiment to conduct in the classroom. Double-stranded RNA is introduced into the worms, where it is chopped into small single-stranded RNA that binds to the target mRNA, thus preventing the translation of the mRNA into protein, and producing a change in phenotype.
The workshop will give teachers the chance to get into the lab and do the experiment, as well as provide a lesson plan, time, and materials to bring the activity into the class.
All instructors, including those at the college level, are welcome to attend, though the lab is designed to be implemented in high schools. Space is limited!
- March 23, 2019
- 9:30 am - 1:30 pm
- Buck Institute
8001 Redwood Blvd
Novato, California 94945