35 results for News
Buck faculty member Pankaj Kapahi spearheads mentoring efforts for disadvantaged children in India
...program has about 60 mentors, most of them drawn from Kapahi’s ever-expanding network of friends, family, and scientific colleagues...
Buck professor Pankaj Kapahi and Reta Haynes go way back
Reta and her now-deceased husband, Bill Haynes, gave $250,000 to jump start the Kapahi lab in 2004, shortly after the young principal investigator came to the Buck...
Advanced Glycation End Products As Drivers of Age-Related Disease
...“If it doesn’t work in simple animals, it’s not going to work in humans...
More details on 500% lifespan extension highlight Buck’s role in moving science forward
...Associate Professor at Nanjing University in China...
Can’t stop binging on fries and BBQ?
...tiny nematode worms, has immense implications for human dietary choices and the propensity to overeat certain foods,” said Buck professor Pankaj Kapahi, PhD, the senior author of the study...
“Fruit Fly” Researcher Joins Buck Institute
...one hundred percent longer than their well-fed peers...
Food is Medicine
Yes, we already know that, says Buck professor Pankaj Kapahi, but what are we doing about it? Hippocrates may or may not have actually said “‘let thy food be...
Hevolution Foundation funds promising pre-clinical studies at the Buck Institute
...his project is aimed at understanding cell-specific aging mechanisms regulated by ketone bodies and their role in human longevity phenotypes...
“Anti-Atkins” Low Protein Diet Extends Lifespan in Flies
...obesity...
Fruit Flies Provide New Clues on How Organisms Make Dietary Choices
...Kapahi...
Eat less and live a long healthy life? Study shows “not in all cases”
...Kapahi lab at the Buck Institute say the devil is in the details...
The Buck’s Impact Circle will support a clinical trial aimed at lowering glycation to slow the aging process
...early-stage research and was glad that Kapahi won the award...
“Obesogens” sound as ominous as they are
...deep dive into the topic of “obesogens,” which are chemicals that make organisms inappropriately increase their fat...
Buck researchers provide a framework to study precision nutrigeroscience
...benefits of dietary restrictions in humans (who generally have a hard time maintaining Spartan diets), the work from the lab of Buck professor Pankaj Kapahi, PhD, suggests that the benefits...
Buck Scientists Identify a Key Protein That May Explain the Anti-Aging and Anti-Cancer Benefits of Dietary Restriction
...and tumor development”, said Buck faculty member Pankaj Kapahi, PhD, lead author of the study...
Uric acid pathologies shorten lifespan in flies, highlighting the need for screening in humans
...and not know it,” says Pankaj Kapahi, PhD, Buck professor and senior author of the paper...
Five-Fold Lifespan Extension in C. Elegans by Combining Mutants
...the nutrient signaling pathway Target of Rapamycin (TOR)...
Does dietary restriction protect against age-related leaky gut?
...to developing intestinal permeability, a condition linked to a variety of human conditions including inflammatory bowel disease...
Buck researchers uncover intriguing connection between diet, eye health and lifespan
...and Buck Institute Professor Pankaj Kapahi, PhD, whose lab has demonstrated for years that fasting and caloric restriction can improve many functions of the body...
Studying Alzheimer’s disease in fruit flies? You bet!
...Here’s how it came together: The first discovery happened in the Kapahi lab where researchers showed that dietary restriction protects fruit flies that have been genetically modified to overexpress tau,...
Retinal scans: A non-invasive, inexpensive method to track human aging
Buck Institute professor Pankaj Kapahi thinks the eye is a window to aging...
Crunching fruit fly and human data via machine learning reveals key metabolites that impact lifespan in both species
...Kapahi, PhD, senior author of the paper...
Buck Scientists Identify How Dietary Restriction Slows Brain Aging & Increases Lifespan
...and age-related neurodegenerative diseases...
Researchers Flip the Switch Between Aging and Development in C. elegans
...into functional proteins...
The Obesity Society says we need to change the way we talk about obesity
Buck professor Pankaj Kapahi agrees The Obesity Society, a professional organization focused on obesity science, treatment and prevention, has called upon researchers and clinicians to use less stigmatizing terminology in...
Rachel Brem, PhD, Joins Buck Institute Faculty
...three labs working on specific aspects of aging or age-related disease...
Meet your hypothalamus. It probably has a lot to do with how you age.
...mice, some of it in collaboration with the Kapahi lab...
Unprecedented Screening of Up to 120,000 Chemical Compounds for Lifespan Extension to Begin
...Kapahi, PhD...
A New Role for Insulin in Cell Survival, Cell Metabolism and Stress Response
...the Buck Institute laboratories of Brian Kennedy and Pankaj Kapahi, all of which point to the importance of translation...
Physical Activity Needed In Order To Reap Benefits Of Dietary Restriction
...primates, however this is the first examination of whether enhanced physical activity is necessary for its beneficial effects,” said Buck faculty Pankaj Kapahi, PhD, who runs the lab where the...
Healing a broken heart: Time, or decreasing expression of a single protein
By Dominican University Graduate Students, Michael Broussalian, Lithgow lab, and Asia Davis-Castillo, Melov lab; Edited by Dr...
Buck Institute awarded $12.7 million from NIH to join SenNet, Cellular Senescence Network
...Malene Hansen, PhD, faculty members David Furman, PhD, Pankaj Kapahi, PhD, Daniel Winer, PhD, and Christopher Benz, MD, as well as assistant research professor Akos Gerencser, PhD, and Senior Staff...
Taurine supplementation extends healthy lifespan in several species
...Kapahi lab, is a first author of the paper...
Faculty Spotlight: Ashley Webb, PhD
...and neurogenesis...
Can getting rid of senescent cells in the brain reduce memory loss?
By: Alejandro Lopez-Ramirez, Lab Manager in the Ellerby lab and Lauren Wimer, Dominican University of California graduate student in the Kapahi lab...
7 results for Focus Areas, Labs & Technologies
Kapahi Lab
...DR response mechanisms exist that remain undiscovered...
Buck Student Aging Symposium
The Buck Student Aging Symposium (BSAS) is an annual internal research conference organized and run by the Graduate Student Society (GSS)...
Impact Circle
Join our Impact Circle for an exclusive look at the pioneering science happening at the Buck Institute...
Human Tissue Mapping Center (TMC)
The NIH has established a Cellular Senescence Network (SenNet) program, comprising of a national “tissue and cell mapping” effort involving 13 research institutes...
GRACE Study
RECRUITING JANUARY 2025 Glycation stress is something that happens when sugars get stuck to proteins in our body, getting in the way of their normal function...
The Paul F. Glenn Center for Biology of Aging Research
Since it was founded in 1965 the Glenn Foundation for Medical Research has supported basic research to better understand the biology that governs normal human aging and related physiological decline,...
Postdoctoral Fellowships
There are three programs that help provide funding for Buck postdocs and their projects...