Hughes Publications

Recent Publications

2011

Pedro Reis-Rodrigues, Gregg Czerwieniec... Robert E Hughes "Proteomic Analysis of Age-dependent Changes in Protein Solubility Identifies Genes that Modulate Lifespan." Aging cell 11:1 120-7

2010

Hemant Varma, Ai Yamamoto... Brent R Stockwell "MUTANT HUNTINGTIN ALTERS CELL FATE IN RESPONSE TO MICROTUBULE DEPOLYMERIZATION VIA GEF-H1-RHOA-ERK PATHWAY." The Journal of biological chemistry 285:48 37445-57

Carlos Gorbea, Gregory Pratt... Martin Rechsteiner "A protein interaction network for ECM29 links the 26S proteasome to molecular motors and endosomal components." The Journal of biological chemistry 285:41 31616-33

John P Miller, Jennifer Holcomb... Lisa M Ellerby "Matrix metalloproteinases are modifiers of huntingtin proteolysis and toxicity in Huntington's disease." Neuron 67:2 199-212

2009

Russell Bell, Alan Hubbard... Robert E Hughes "A human protein interaction network shows conservation of aging processes between human and invertebrate species." PLoS Genet. 5:3 e1000414

2008

Marissa Vignali, Anastasia McKinlay... Stanley Fields "Interaction of an atypical Plasmodium falciparum ETRAMP with human apolipoproteins." Malar. J. 7 211

Eliana Romero, Guang-Ho Cha... Juan Botas "Suppression of neurodegeneration and increased neurotransmission caused by expanded full-length huntingtin accumulating in the cytoplasm." Neuron 57:1 27-40

2007

Linda S Kaltenbach, Eliana Romero... Robert E Hughes "Huntingtin interacting proteins are genetic modifiers of neurodegeneration." PLoS Genet. 3:5 e82

2005

Douglas J LaCount, Marissa Vignali... Robert E Hughes "A protein interaction network of the malaria parasite Plasmodium falciparum." Nature 438:7064 103-7

2002

Robert E Hughes, ... Robert E Hughes "Polyglutamine disease: acetyltransferases awry." Curr. Biol. 12:4 R141-3

2001

R E Hughes, R S Lo... S Fields "Altered transcription in yeast expressing expanded polyglutamine." Proc. Natl. Acad. Sci. U.S.A. 98:23 13201-6

R E Hughes, J M Olson... J M Olson "Therapeutic opportunities in polyglutamine disease." Nat. Med. 7:4 419-23

2000

P Uetz, R E Hughes... R E Hughes "Systematic and large-scale two-hybrid screens." Curr. Opin. Microbiol. 3:3 303-8

1998

R E Hughes, P S Brzovic... J B Hurley "Ca2+-dependent conformational changes in bovine GCAP-2." Protein Sci. 7:12 2675-80

1997

E V Olshevskaya, R E Hughes... A M Dizhoor "Calcium binding, but not a calcium-myristoyl switch, controls the ability of guanylyl cyclase-activating protein GCAP-2 to regulate photoreceptor guanylyl cyclase." J. Biol. Chem. 272:22 14327-33

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