Ellerby Publications

Recent Publications

2011

Xin Cong, Jason M Held... Lisa M Ellerby "Mass spectrometric identification of novel lysine acetylation sites in huntingtin." Molecular & cellular proteomics : MCP 10:10 M111.009829

2010

Melissa J Leyva, Francesco Degiacomo... Jonathan A Ellman "Identification and Evaluation of Small Molecule Pan-Caspase Inhibitors in Huntington's Disease Models." Chem. Biol. 17:11 1189-200

John P Miller, Jennifer Holcomb... Lisa M Ellerby "Matrix metalloproteinases are modifiers of huntingtin proteolysis and toxicity in Huntington's disease." Neuron 67:2 199-212

Carlotta Duncan, Theodora Papanikolaou... Lisa M Ellerby "Autophagy: polyQ toxic fragment turnover." Autophagy 6:2 312-4

Christian Landles, Kirupa Sathasivam... Gillian P Bates "Proteolysis of mutant huntingtin produces an exon 1 fragment that accumulates as an aggregated protein in neuronal nuclei in Huntington disease." J. Biol. Chem. 285:12 8808-23

Ningzhe Zhang, Mahru C An... Lisa M Ellerby "Characterization of Human Huntington's Disease Cell Model from Induced Pluripotent Stem Cells." PLoS Curr 2 RRN1193

2009

Shona Mookerjee, Theodora Papanikolaou... Lisa M Ellerby "Posttranslational modification of ataxin-7 at lysine 257 prevents autophagy-mediated turnover of an N-terminal caspase-7 cleavage fragment." J. Neurosci. 29:48 15134-44

Juliette Gafni, Xin Cong... Lisa M Ellerby "Calpain-1 cleaves and activates caspase-7." J. Biol. Chem. 284:37 25441-9

Theodora Papanikolaou, Lisa M Ellerby... Lisa M Ellerby "IGF-1: elixir for motor neuron diseases." Neuron 63:3 277-8

Jessica E Young, Gwenn A Garden... Albert R La Spada "Polyglutamine-expanded androgen receptor truncation fragments activate a Bax-dependent apoptotic cascade mediated by DP5/Hrk." J. Neurosci. 29:7 1987-97

2007

Jessica E Young, Launce Gouw... Lisa M Ellerby "Proteolytic cleavage of ataxin-7 by caspase-7 modulates cellular toxicity and transcriptional dysregulation." J. Biol. Chem. 282:41 30150-60

Adil A Khan, Yunjuan Sun... David A Greenberg "A neuroglobin-overexpressing transgenic mouse." Gene 398:1-2 172-6

Linda S Kaltenbach, Eliana Romero... Robert E Hughes "Huntingtin interacting proteins are genetic modifiers of neurodegeneration." PLoS Genet. 3:5 e82

Jorge M A Oliveira, Mika B Jekabsons... David G Nicholls "Mitochondrial dysfunction in Huntington's disease: the bioenergetics of isolated and in situ mitochondria from transgenic mice." J. Neurochem. 101:1 241-9

2006

Adil A Khan, Yaoming Wang... David A Greenberg "Neuroglobin-overexpressing transgenic mice are resistant to cerebral and myocardial ischemia." Proc. Natl. Acad. Sci. U.S.A. 103:47 17944-8

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