Buck Institute faculty Judith Campisi receives first Olav Thon Foundation Prize

Norway’s largest charitable foundation bestows cash prize for Campisi’s pioneering work on cancer and aging

January 21, 2015/NOVATO, CA: The Olav Thon Foundation, Norway’s largest charitable organization, has awarded its first international research award in the medical and natural sciences to Buck Institute faculty Judith Campisi, PhD, and Tel Aviv University Professor Yosef Shiloh. The prize money, 5,000,000 Norwegian Kroner (approximately $660,000) was split between the two of them. Campisi will go to Oslo to receive the award at a March 5th ceremony.

Campisi was recognized for her pioneering work on the connection between aging and cancer and the process of cellular senescence, which is linked to chronic inflammation. According to the Foundation, “Campisi’s research is highly acclaimed in the international community of scientists, occupying the field between molecular biology and age-related cell degeneration. Through her outstanding contributions she has contributed significantly in turning ‘ageing’ into an exciting and prestigious domain of research.”

“Scientists are always heartened to receive recognition for their work,” said Campisi, who is a Fellow of the American Association for the Advancement of Science and the recipient of numerous awards including the Longevity Prize from the Ipsen Foundation. “I thank the Foundation for their support and for appreciating the need to advance the field of aging research.” According to the Foundation, “Considering the aging of the population, it is vital to secure for our seniors a healthy life, not only for their own sense of wellbeing but also for their being able to contribute to their social environment. This is where the larger promise of Campisi’s research lies.”

Cancer, aging and inflammation
Campisi’s highly acclaimed research integrates the genetic, environmental and evolutionary forces that result in aging and age-related diseases, and identifies pathways that can be modified to mitigate basic aging processes.

Campisi is widely recognized for the emerging focus on “inflamm-aging” based on her work on senescent cells --– a process whereby cells permanently lose the ability to divide when they are stressed. Senescence suppresses cancer by halting the growth of premalignant cells, but it is also suspected of driving the aging process. Senescent cells, which accumulate over time, release a continual cascade of inflammatory cytokines, chemokines, growth factors and proteases. It is a process that sets up the surrounding tissue for a host of maladies including arthritis, atherosclerosis and late life cancer.

About the Buck Institute for Research on Aging

The Buck Institute is the U.S.’s first independent research organization devoted to Geroscience – focused on the connection between normal aging and chronic disease. Based in Novato, CA, The Buck is dedicated to extending “Healthspan”, the healthy years of human life and does so utilizing a unique interdisciplinary approach involving laboratories studying the mechanisms of aging and those focused on specific diseases. Buck scientists strive to discover new ways of detecting, preventing and treating age-related diseases such as Alzheimer’s and Parkinson’s, cancer, cardiovascular disease, macular degeneration, osteoporosis, diabetes and stroke.  In their collaborative research, they are supported by the most recent developments in genomics, proteomics, bioinformatics and stem cell technologies. For more information: www.thebuck.org

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