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Gordon J. Lithgow

Selected Publications

  • Fisher AL, Page KE, Lithgow GJ, Nash L. The C. elegans K10C2.4 gene encodes a member of the fumarylacetoacetate hydrolase family. A C. elegans model of type I tyrosinemia. J Biol Chem. 2008 Jan 28; [Epub ahead of print] PMID: 18227072
     
  • McColl G, Killilea DW, Hubbard AE, Vantipalli MC, Melov S, Lithgow GJ.Pharmacogenetic analysis of lithium-induced delayed aging in Caenorhabditis elegans.J Biol Chem. 2008 Jan 4;283(1):350-7. Epub 2007 Oct 24. PMID: 17959600 [PubMed - in process]
     
  • Pan KZ, Palter JE, Rogers AN, Olsen A, Chen D, Lithgow GJ, Kapahi P. Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans. Aging Cell. 2007 Feb;6(1):111-9. PMID: 17266680
     
  • Lithgow GJ. Why aging isn't regulated: a lamentation on the use of language in aging literature. Exp Gerontol. 2006 Oct;41(10):890-3. Epub 2006 Sep 7. Review. PMID: 16959457
     
  • Held JM, White MP, Fisher AL, Gibson BW, Lithgow GJ, Gill MS. DAF-12-dependent rescue of dauer formation in Caenorhabditis elegans by (25S)-cholestenoic acid. Aging Cell. 2006 Aug;5(4):283-91.
     
  • Olsen A, Vantipalli MC, Lithgow GJ. Lifespan extension of Caenorhabditis elegans following repeated mild hormetic heat treatments.Biogerontology. 2006 Aug;7(4):221-30.
     
  • Olsen A, Vantipalli MC, Lithgow GJ. Checkpoint proteins control survival of the postmitotic cells in Caenorhabditis elegans. Science. 2006 Jun 2;312(5778):1381-5.
     
  • Fisher AL, Lithgow GJ. The nuclear hormone receptor DAF-12 has opposing effects on Caenorhabditis elegans lifespan and regulates genes repressed in multiple long-lived worms. Aging Cell. 2006 Apr;5(2):127-38.
     
  • Lin YT, Hoang H, Hsieh SI, Rangel N, Foster AL, Sampayo JN, Lithgow GJ, Srinivasan C. Manganous ion supplementation accelerates wild type development, enhances stress resistance, and rescues the life span of a short-lived Caenorhabditis elegans mutant. Free Radic Biol Med. 2006 Apr 1;40(7):1185-93.
     
  • McColl G, Vantipalli MC, Lithgow GJ. The C. elegans ortholog of mammalian Ku70, interacts with insulin-like signaling to modulate stress resistance and life span. FASEB J. 2005 Oct;19(12):1716-8.
     
  • Jenkins, N., McColl, G., and Lithgow, G. J. 2004. The fitness cost of extended lifespan in Caenorhabditis elegans. Proceedings of the Royal Society 271:2523-2526.
     
  • Gill, M. S., Held, J. M., Fisher, A. L., Gibson, B. W., and Lithgow, G. J. 2004. Lipophilic regulator of a developmental switch in Caenorhabditis elegans. Aging Cell 3:413-421.
     
  • Sampayo, J.N., Olsen A., and Lithgow G.J. 2003. Oxidative stress in Caenorhabditis elegans: protective effects of superoxide dismutase / catalase mimetics.Aging Cell 2:319-326
     
  • Sampayo, J. N., Gill, M. S., and Lithgow, G. J. 2003. Oxidative stress and aging— the use of superoxide dismutase/catalase mimetics to extend lifespan.Biochem Soc Trans 31:1305–1307.
     
  • Gill, M.S., Olsen, A., Sampayo, J.N., and Lithgow, G.J. 2003. An automated high-throughput assay for survival of the nematode Caenorhabditis elegans. Free Rad. Biol. Med. 35:558-565.
  
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